SCHEMBL5670569

SCHEMBL5670569

CCN(CC1CCCC1)c1ccc2c(c1CCc1cc(C#N)cc(C(F)(F)F)c1)CCCC2

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 1/20 0.31
AR P10275 1/20 0.31
APAF1 O14727 1/20 0.31
IDE P14735 1/20 0.31
RXRA P19793 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5672226 0.90 TACR1 (0.31) CCR2RXRARXRG
SCHEMBL5672098 0.88
SCHEMBL5148310 0.86 RXRA (0.34) CCR2RXRARXRG
SCHEMBL5670667 0.84 RXRA (0.34) CCR2RXRARXRG
SCHEMBL1897159 0.84 CETP (0.41)
SCHEMBL5670023 0.83 RXRA (0.34) CCR2ARRXRARXRG
SCHEMBL1897741 0.82 CETP (0.41) CCR2
SCHEMBL1899153 0.81 CETP (0.41)
SCHEMBL5149805 0.79 CCR2 (0.33) CCR2RXRARXRG
SCHEMBL5147203 0.78 CCR2 (0.33) CCR2RXRARXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1670446-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2006-06-21 EP claimed
WO-2005030185-A2 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION JAPAN TOBACCO INC. (JP) 2005-04-07 WO claimed