Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5432549 | 0.84 | HTR2B (0.47) | KDM4EALDH1A1SMN1; SMN2HTR2BPKM | |
| SCHEMBL5424266 | 0.84 | KDM4E (0.67) | HDAC4MEF2DKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL15121483 | 0.80 | HTR2B (0.45) | HDAC4KDM4EALDH1A1SMN1; SMN2HTR2B | |
| SCHEMBL5670848 | 0.80 | HDAC4 (0.60) | HDAC4MEF2DKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5425068 | 0.79 | MAOB (0.58) | SMN1; SMN2CYP3A4HPGDCYP2C19MAOB | |
| SCHEMBL5443386 | 0.79 | P4HB (0.56) | KDM4EHTR2BPKMMAOBMAOA | |
| SCHEMBL5672084 | 0.79 | HTR2B (0.47) | HDAC4MEF2DKDM4EALDH1A1HTR2B | |
| SCHEMBL5441731 | 0.74 | NFE2L2 (0.52) | KDM4EALDH1A1SMN1; SMN2HTR2BMAOB | |
| SCHEMBL2536091 | 0.72 | MAOA (0.57) | HDAC4MEF2DALDH1A1CYP3A4HPGD | |
| SCHEMBL16953003 | 0.72 | CYP2C19 (0.46) | HDAC4MEF2DKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646371-A2 | ANTIVIRAL COMPOUNDS AND METHODS | Biotron Limited (AU) | 2006-04-19 | — | — | EP | claimed |
| WO-2004112687-A2 | ANTIVIRAL ACYLGUANIDINE COMPOUNDS AND METHODS | BIOTRON LIMITED (AU) | 2004-12-29 | — | — | WO | claimed |