SCHEMBL5670853

SCHEMBL5670853

C/C(=C\CCNC(=O)Nc1ccc(O)cc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
CNR1 P21554 2/20 0.46
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
MAPT P10636 3/20 0.45
CYP3A4 P08684 2/20 0.45
CA12 O43570 1/20 0.45
BRD4 O60885 1/20 0.45
NR1I2 O75469 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
MB P02144 1/20 0.45
CYP1A1 P04798 1/20 0.45
CA3 P07451 1/20 0.45
RARG P13631 1/20 0.45
TSHR P16473 1/20 0.45
ALOX5AP P20292 1/20 0.45
CA4 P22748 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4942266 1.00 MAOA (0.46) MAOAMAOBCNR1ALDH1A1MEN1
SCHEMBL7096382 0.91 EPHX1 (0.48) MAOAMAOBCNR1ALDH1A1MEN1
SCHEMBL7096379 0.91 EPHX1 (0.48) MAOAMAOBCNR1ALDH1A1MEN1
SCHEMBL8550844 0.89 ALDH1A1 (0.53) CNR1ALDH1A1MEN1KMT2ACYP3A4
SCHEMBL8550837 0.89 ALDH1A1 (0.53) CNR1ALDH1A1MEN1KMT2ACYP3A4
SCHEMBL8549835 0.88 EPHX1 (0.54) ALDH1A1MEN1KMT2AMAPTCYP3A4
SCHEMBL8549827 0.88 EPHX1 (0.54) ALDH1A1MEN1KMT2AMAPTCYP3A4
SCHEMBL31122213 0.87 CNR1 (0.44) CNR1ALDH1A1MEN1KMT2AMAPT
SCHEMBL8550248 0.87 NAMPT (0.47) CNR1ALDH1A1MEN1KMT2AMAPT
SCHEMBL8550251 0.87 NAMPT (0.47) CNR1ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822206-B2 Copolymers for near-infrared radiation-sensitive coating compositions for positive-working thermal lithographic printing plates MYLAN GROUP (VN) 2017-11-21 US disclosed
EP-2566900-B1 COPOLYMERS FOR NEAR-INFRARED RADIATION-SENSITIVE COATING COMPOSITIONS FOR POSITIVE-WORKING THERMAL LITHOGRAPHIC PRINTING PLATES MYLAN GROUP (VN) 2016-02-17 EP disclosed
US-20140221591-A1 COPOLYMERS FOR NEAR-INFRARED RADIATION-SENSITIVE COATING COMPOSITIONS FOR POSITIVE-WORKING THERMAL LITHOGRAPHIC PRINTING PLATES MYLAN GROUP (VN) 2014-08-07 US disclosed
EP-1368413-A4 TWO-LAYER IMAGEABLE ELEMENT COMPRISING THERMALLY REVERSIBLE POLYMERS KODAK POLYCHROME GRAPHICS LLC (US) 2006-08-02 EP disclosed
US-6902860-B2 Polyurethanes KODAK POLYCHROME GRAPHICS LLC (US) 2005-06-07 US disclosed
US-20040023155-A1 Polymeric molecules that comprises a quadruple hydrogen bonding unit, particularly from 6-methylisocytosine reacted with a diisocyanate; acrylic, phenolic, polyester and/or polyurethane units KODAK POLYCHROME GRAPHICS, LLC 2004-02-05 US disclosed
EP-1368413-A1 TWO-LAYER IMAGEABLE ELEMENT COMPRISING THERMALLY REVERSIBLE POLYMERS Kodak Polychrome Graphics (US) 2003-12-10 EP disclosed
EP-0737896-B1 Photosensitive composition and photosensitive planographic printing plate KODAK POLYCHROME GRAPHICS JP (JP) 2003-08-27 EP disclosed
US-20020160299-A1 Polyurethanes KODAK POLYCHROME GRAPHICS, L.L.C. (US) 2002-10-31 US disclosed
WO-2002053627-A1 TWO-LAYER IMAGEABLE ELEMENT COMPRISING THERMALLY REVERSIBLE POLYMERS KODAK POLYCHROME GRAPHICS, L.L.C. (US) 2002-07-11 WO disclosed
US-5731127-A WEAR RESISTANCE, SOLVENT RESISTANCE DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-03-24 US disclosed
EP-0737896-A2 Photosensitive composition and photosensitive planographic printing plate DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020160299-A1 Polyurethanes PUF60, PCBP1, PARG MAOA 2612/4885MAOB 3696/4885CNR1 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.