Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.63 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672105 | 0.90 | HRH3 (0.50) | HRH3SSTR5LTA4HNPC1RAB9A | |
| SCHEMBL5670141 | 0.81 | HRH3 (0.49) | HRH3LTA4HKDM4EHTTKMT2A | |
| SCHEMBL5670771 | 0.75 | HRH3 (0.43) | HRH3SMN1; SMN2KDM4EHTTALDH1A1 | |
| SCHEMBL21840806 | 0.73 | HRH3 (0.60) | HRH3RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30438225 | 0.73 | HRH3 (0.60) | HRH3RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL6750836 | 0.73 | HRH3 (0.58) | HRH3SSTR5LTA4HNPC1RAB9A | |
| SCHEMBL4688871 | 0.72 | LTA4H (0.97) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20748052 | 0.72 | LTA4H (0.97) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3581020 | 0.71 | NPC1 (0.87) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14970586 | 0.71 | NPC1 (0.87) | HRH3LTA4HNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542686-A4 | ARYL SUBSTITUTED HYDANTOIN COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | EURO CELTIQUE SA (LU) | 2006-10-18 | — | — | EP | claimed |
| EP-1542686-A2 | ARYL SUBSTITUTED HYDANTOIN COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | Euro-Celtique S.A. (LU) | 2005-06-22 | — | — | EP | claimed |
| WO-2004010950-A2 | ARYL SUBSTITUTED HYDANTOIN COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2004-02-05 | — | — | WO | claimed |
| EP-1542686-A4 | ARYL SUBSTITUTED HYDANTOIN COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | EURO CELTIQUE SA (LU) | 2006-10-18 | — | — | EP | disclosed |
| EP-1542686-A2 | ARYL SUBSTITUTED HYDANTOIN COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | Euro-Celtique S.A. (LU) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004010950-A2 | ARYL SUBSTITUTED HYDANTOIN COMPOUNDS AND THEIR USE AS SODIUM CHANNEL BLOCKERS | EURO-CELTIQUE S.A. (LU) | 2004-02-05 | — | — | WO | disclosed |