Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13071968 | 0.78 | HSD17B10 (0.33) | LMNATSHRMAPTHSD17B10 | |
| Iodide SCHEMBL17259189 | 0.72 | DYRK1A (0.37) | LMNATSHRHTTL3MBTL1MAPT | |
| SCHEMBL3634283 | 0.67 | MEN1 (0.34) | LMNATSHRHTT | |
| SCHEMBL18802975 | 0.65 | PIM1 (0.39) | TSHRHTTHSD17B10 | |
| SCHEMBL3640575 | 0.65 | DGAT1 (0.31) | — | |
| SCHEMBL6738708 | 0.63 | — | — | |
| SCHEMBL27077549 | 0.63 | ALDH1A1 (0.47) | LMNAHSD17B10 | |
| SCHEMBL3637817 | 0.61 | DGAT1 (0.33) | — | |
| SCHEMBL3402580 | 0.61 | ADORA2A (0.40) | HSD17B10 | |
| SCHEMBL6839602 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |