Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27077549 | 0.79 | ALDH1A1 (0.47) | HSD17B10LMNAALDH1A1RXFP1KDM4E | |
| SCHEMBL5672991 | 0.78 | LMNA (0.32) | HSD17B10LMNAMAPTTSHR | |
| SCHEMBL9771946 | 0.75 | MAPT (0.39) | HSD17B10LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL3402580 | 0.75 | ADORA2A (0.40) | HSD17B10KDM4E | |
| SCHEMBL5180079 | 0.74 | MAPT (0.36) | MAPTALDH1A1RXFP1 | |
| SCHEMBL27077556 | 0.74 | ALDH1A1 (0.40) | ALDH1A1RXFP1KDM4E | |
| SCHEMBL15007536 | 0.71 | SMN1; SMN2 (0.51) | HSD17B10MAPTTSHRALDH1A1KDM4E | |
| SCHEMBL10341293 | 0.71 | ALDH1A1 (0.32) | HSD17B10LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL18802975 | 0.69 | PIM1 (0.39) | HSD17B10TSHRALDH1A1KDM4E | |
| SCHEMBL15007607 | 0.64 | CSNK2A2 (0.39) | HSD17B10LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3157904-B1 | ANTI-INFECTIVE COMPOUNDS | PASTEUR INSTITUT KOREA (KR) | 2020-11-18 | — | — | EP | disclosed |
| US-20180044316-A1 | POTENTIATORS OF BETA-LACTAM ANTIBIOTICS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2018-02-15 | — | — | US | disclosed |
| US-20170121349-A1 | Anti-Infective Compounds | INSTITUT PASTEUR KOREA (KR) | 2017-05-04 | — | — | US | disclosed |
| WO-2015193506-A1 | ANTI-INFECTIVE COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2015-12-23 | — | — | WO | disclosed |
| US-20100297035-A1 | Thiazole Amides, Imidazole Amides and Related Analogues | LIGAND PHARMACEUTICALS, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297035-A1 | Thiazole Amides, Imidazole Amides and Related Analogues | HRH3, HRH4, HRH2 | HSD17B10 3129/4885LMNA 4548/4885MAPT 342/4885 |
| US-20180044316-A1 | POTENTIATORS OF BETA-LACTAM ANTIBIOTICS | CREB1, PPP6R1, PPP1R10 | HSD17B10 3489/4885LMNA 2931/4885MAPT 4421/4885 |
| US-20170121349-A1 | Anti-Infective Compounds | FNTB, LSS, PGLS | HSD17B10 1899/4885LMNA 3151/4885MAPT 2813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.