Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673864 | 0.99 | PDE2A (0.39) | HPGDPDE2APARP10PARP15GRM2 | |
| SCHEMBL5672581 | 0.88 | ALOX5AP (0.40) | HPGDPARP10PARP15SLC16A3SLC16A1 | |
| SCHEMBL5672574 | 0.88 | ALOX5AP (0.40) | HPGDPARP10PARP15SLC16A3SLC16A1 | |
| SCHEMBL5672911 | 0.87 | ALOX5AP (0.40) | HPGDPDE2APARP10PARP15SLC16A3 | |
| SCHEMBL5672915 | 0.87 | ALOX5AP (0.40) | HPGDPDE2APARP10PARP15SLC16A3 | |
| SCHEMBL5674041 | 0.81 | ALDH1A1 (0.37) | PDE2AMAOAMAOB | |
| SCHEMBL5672933 | 0.80 | BCL2L1 (0.44) | ALOX5AP | |
| SCHEMBL5672936 | 0.80 | BCL2L1 (0.44) | ALOX5AP | |
| SCHEMBL5214619 | 0.80 | PPARG (0.39) | PDE2A | |
| SCHEMBL5672537 | 0.79 | BCL2L1 (0.43) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |