Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | ACACA | Q13085 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214619 | 0.94 | PPARG (0.39) | ALDH1A1VDRPPARGMEN1KMT2A | |
| SCHEMBL5674030 | 0.86 | KDM4E (0.39) | ALDH1A1PPARGMEN1KMT2APTGS1 | |
| SCHEMBL5674028 | 0.86 | KDM4E (0.39) | ALDH1A1PPARGMEN1KMT2APTGS1 | |
| SCHEMBL5675388 | 0.84 | PPARG (0.38) | ALDH1A1PPARGMAPTTHRBL3MBTL1 | |
| SCHEMBL5673966 | 0.84 | S1PR1 (0.49) | ALDH1A1VDRMEN1KMT2AMAOA | |
| SCHEMBL5673830 | 0.83 | PPARG (0.38) | VDRPPARGMAPTTHRBL3MBTL1 | |
| SCHEMBL5673864 | 0.82 | PDE2A (0.39) | MAOAMAOBPDE2A | |
| SCHEMBL5675559 | 0.82 | AGTR1 (0.40) | MAPTTHRBL3MBTL1NPSR1 | |
| SCHEMBL5673752 | 0.81 | HPGD (0.41) | MAOAMAOBPDE2A | |
| SCHEMBL5675518 | 0.81 | PPARG (0.37) | ALDH1A1VDRPPARGTHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |