Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 5/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214619 | 0.91 | PPARG (0.39) | PPARGL3MBTL1THRBTHRAKDM4E | |
| SCHEMBL5673830 | 0.89 | PPARG (0.38) | PPARGL3MBTL1THRBTHRAMAPT | |
| SCHEMBL5675518 | 0.87 | PPARG (0.37) | PPARGL3MBTL1THRBTHRAKDM4E | |
| SCHEMBL5673021 | 0.86 | PPARG (0.39) | PPARGTHRBTHRAKDM4EP4HB | |
| SCHEMBL5673028 | 0.86 | PPARG (0.39) | PPARGTHRBTHRAKDM4EP4HB | |
| SCHEMBL5674041 | 0.84 | ALDH1A1 (0.37) | PPARGL3MBTL1THRBNPSR1ALDH1A1 | |
| SCHEMBL5675559 | 0.83 | AGTR1 (0.40) | L3MBTL1THRBTHRAKDM4EP4HB | |
| SCHEMBL5673965 | 0.81 | THRB (0.38) | L3MBTL1THRBTHRA | |
| SCHEMBL5216749 | 0.80 | PPARG (0.40) | PPARGTHRBTHRA | |
| SCHEMBL5216738 | 0.80 | PPARG (0.40) | PPARGTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7060721-B1 | Imidazole compounds and medicinal use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2006-06-13 | — | — | US | disclosed |
| EP-1142879-A1 | IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |