Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635556 | 0.89 | KDM1A (0.46) | KDM1ACNR1CNR2HDAC2HDAC1 | |
| SCHEMBL4634695 | 0.85 | HDAC2 (0.48) | KDM1ACNR1CNR2HDAC2HDAC1 | |
| SCHEMBL5672765 | 0.83 | KDM1A (0.48) | KDM1ACNR1CNR2HDAC2HDAC1 | |
| SCHEMBL14357682 | 0.83 | KDM1A (0.48) | KDM1ACNR1CNR2HDAC2HDAC1 | |
| SCHEMBL4634666 | 0.82 | HDAC2 (0.48) | KDM1ACNR1CNR2HDAC2HDAC1 | |
| SCHEMBL4634716 | 0.81 | HSD11B1 (0.41) | KMT2A | |
| SCHEMBL4634595 | 0.81 | KDM1A (0.46) | KDM1ACNR1CNR2HDAC2HDAC1 | |
| Hydrochloric Acid SCHEMBL5812318 | 0.81 | HDAC2 (0.47) | KDM1ACNR1CNR2HDAC2HDAC1 | |
| SCHEMBL3356420 | 0.81 | KDM1A (0.46) | KDM1ACNR1CNR2HDAC2HDAC1 | |
| SCHEMBL2185224 | 0.81 | KDM1A (0.46) | KDM1ACNR1CNR2HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060167044-A1 | Piperidine derivatives and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167044-A1 | Piperidine derivatives and their use as anti-inflammatory agents | CCR1, CCR2, CCR3 | KDM1A 3174/4885CNR1 33/4885CNR2 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.