Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5674643 | 0.81 | KDM1A (0.45) | KMT2A | |
| SCHEMBL4634537 | 0.80 | CYP46A1 (0.50) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL5810883 | 0.77 | HSD11B1 (0.43) | HSD11B1ALDH1A1POLB | |
| SCHEMBL2798597 | 0.75 | ALDH1A1 (0.43) | HSD11B1ALDH1A1POLB | |
| SCHEMBL4634991 | 0.75 | HSD11B1 (0.41) | HSD11B1KMT2AFAAHALDH1A1POLB | |
| SCHEMBL5807513 | 0.73 | HTT (0.41) | HSD11B1FAAHALDH1A1 | |
| SCHEMBL4634337 | 0.73 | OPRM1 (0.43) | HSD11B1KMT2A | |
| SCHEMBL4635362 | 0.73 | HSD11B1 (0.40) | HSD11B1KMT2AFAAHALDH1A1POLB | |
| SCHEMBL4634957 | 0.72 | HSD11B1 (0.44) | HSD11B1KMT2AALDH1A1POLB | |
| SCHEMBL21391900 | 0.71 | FAAH (0.65) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928829-A1 | PIPERIDINE DERIVATIVES AS ANTAGONISTS OF THE CC CHEMOKINE RECEPTOR CCR1 AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Schering Aktiengesellschaft (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2006066948-A1 | PIPERIDINE DERIVATIVES AS ANTAGONISTS OF THE CC CHEMOKINE RECEPTOR CCR1 AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-06-29 | — | — | WO | disclosed |