Hydrochloric Acid

Hydrochloric Acid

SCHEMBL5674656

C=C(C)C(=O)OCC[n+]1ccccc1.[Cl-]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 2/20 0.34
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.44
ALDH1A1 P00352 3/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP2 P42575 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSPD1 P10809 1/20 0.35
RAD52 P43351 1/20 0.35
HSPE1 P61604 1/20 0.35
BCHE P06276 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10784485 1.00 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL27956289 0.94 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10785084 0.92 THRB (0.40) THRBTSHRALDH1A1POLBAPEX1
Hydrochloric Acid SCHEMBL28785382 0.88 TSHR (0.53) TSHRALDH1A1POLBAPEX1HTT
Hydrochloric Acid SCHEMBL7055391 0.87 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL6860941 0.87 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
Hydrochloric Acid SCHEMBL1032458 0.87 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL6397609 0.87 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
Hydrochloric Acid SCHEMBL9132796 0.87 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
Hydrochloric Acid SCHEMBL346360 0.87 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4097155-B1 ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF CLEARLAB SG PTE LTD (SG) 2025-08-20 EP disclosed
US-12037463-B2 Antimicrobial ophthalmic devices comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-16 US disclosed
US-12024597-B2 Wound dressings comprising polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2024-07-02 US disclosed
US-20230227613-A1 ANTIMICROBIAL OPHTHALMIC DEVICES COMPRISING POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF CLEARLAB SG PTE LTD (SG) 2023-07-20 US disclosed
US-20230212357-A1 WOUND DRESSINGS COMPRISING POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF CLEARLAB SG PTE LTD (SG) 2023-07-06 US disclosed
US-11649325-B2 Actinically-crosslinkable polysiloxane-polyglycerol block copolymers and methods of making and use thereof Clearlab Sg Pte Ltd. (SG) 2023-05-16 US disclosed
EP-4097155-A1 ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF Clearlab SG Pte Ltd (SG) 2022-12-07 EP disclosed
US-20210246270-A1 ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF Clearlab Sg Pte Ltd. (SG) 2021-08-12 US disclosed
WO-2021154692-A1 ACTINICALLY-CROSSLINKABLE POLYSILOXANE-POLYGLYCEROL BLOCK COPOLYMERS AND METHODS OF MAKING AND USE THEREOF Clearlab Sg Pte Ltd. (SG) 2021-08-05 WO disclosed
US-7056650-B2 Thermally developable materials containing cationic overcoat polymer EASTMAN KODAK COMPANY (US) 2006-06-06 US disclosed
US-7049054-B2 Thermally developable materials containing ionic polymer interlayer EASTMAN KODAK COMPANY (US) 2006-05-23 US disclosed
US-20060051713-A1 Thermally developable materials containing cationic overcoat polymer EASTMAN KODAK COMPANY 2006-03-09 US disclosed
US-20060051712-A1 THERMALLY DEVELOPABLE MATERIALS CONTAINING IONIC POLYMER INTERLAYER EASTMAN KODAK COMPANY 2006-03-09 US disclosed