Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 17/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6182713 | 1.00 | PTGER3 (0.49) | PTGER3HPGDNPSR1L3MBTL1PPARG | |
| SCHEMBL5675520 | 0.91 | PTGER3 (0.41) | PTGER3HPGDNPSR1L3MBTL1PTGER4 | |
| SCHEMBL5675528 | 0.91 | PTGER3 (0.41) | PTGER3HPGDNPSR1L3MBTL1PTGER4 | |
| SCHEMBL6183869 | 0.90 | PTGER3 (0.47) | PTGER3HPGDNPSR1L3MBTL1PPARG | |
| SCHEMBL6183880 | 0.90 | PTGER3 (0.47) | PTGER3HPGDNPSR1L3MBTL1PPARG | |
| SCHEMBL5673729 | 0.87 | HDAC1 (0.41) | PTGER3 | |
| SCHEMBL5215201 | 0.87 | PTGER3 (0.41) | PTGER3 | |
| SCHEMBL5673734 | 0.87 | HDAC1 (0.41) | PTGER3 | |
| SCHEMBL5215186 | 0.87 | PTGER3 (0.41) | PTGER3 | |
| SCHEMBL5673810 | 0.85 | PTGES (0.45) | PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000932-B9 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2005-12-28 | — | — | EP | disclosed |
| EP-1000932-B1 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6242474-B1 | SULFONYLCARBAMOYLALKYLIMIDAZOLE DERIVATIVES; ANTIDIABETIC AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1000932-A1 | AROMATIC RING DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-17 | — | — | EP | disclosed |