Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567366 | 1.00 | HTT (0.51) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL12537093 | 0.84 | HTT (0.55) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL3976930 | 0.82 | EPHX2 (0.43) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13843599 | 0.82 | TGM2 (0.54) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL3978073 | 0.82 | ALDH1A1 (0.41) | LMNA | |
| SCHEMBL567024 | 0.79 | ALDH1A1 (0.43) | LMNAKMT2A | |
| SCHEMBL22525114 | 0.79 | IDO1 (0.62) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL18254066 | 0.77 | HTT (0.81) | HTTTGM2KEAP1NFE2L2LMNA | |
| SCHEMBL536617 | 0.77 | GLA (0.47) | MEN1KMT2A | |
| SCHEMBL567327 | 0.77 | GLA (0.47) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035341-A1 | PROCEDE DE POLYMERISATION PAR VOIE CATALYTIQUE DE 1,4-DIOXANES-2,5-DIONES ET LES POLYMERES CORRESPONDANTS | MINASOLVE (FR) | 2012-02-09 | — | — | US | disclosed |
| WO-2010100390-A1 | CATALYTIC POLYMERIZATION METHOD FOR 1,4-DIOXANE-2,5-DIONES, AND CORRESPONDING POLYMERS | MINASOLVE (FR) | 2010-09-10 | — | — | WO | disclosed |