SCHEMBL567327

SCHEMBL567327

O=C(C[C@@H]1OC(=O)COC1=O)OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.47
ALDH1A1 P00352 3/20 0.45
MAPK1 P28482 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
USP2 O75604 1/20 0.44
CDC25B P30305 1/20 0.39
KMT2A Q03164 3/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CASP1 P29466 2/20 0.38
CASP3 P42574 2/20 0.38
CASP7 P55210 2/20 0.38
CASP6 P55212 2/20 0.38
CASP8 Q14790 2/20 0.38
MEN1 O00255 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536617 1.00 GLA (0.47) GLAALDH1A1MAPK1L3MBTL1USP2
SCHEMBL567494 0.87 ALDH1A1 (0.43) GLAALDH1A1MAPK1L3MBTL1USP2
SCHEMBL567024 0.87 ALDH1A1 (0.43) GLAALDH1A1MAPK1L3MBTL1USP2
SCHEMBL3978073 0.85 ALDH1A1 (0.41) GLAALDH1A1MAPK1L3MBTL1USP2
SCHEMBL3976930 0.83 EPHX2 (0.43) GLAALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL567091 0.78 LMNA (0.49) CDC25B
SCHEMBL567665 0.78 LMNA (0.49) CDC25B
SCHEMBL567608 0.77 HTT (0.51) KMT2AMEN1
SCHEMBL567366 0.77 HTT (0.51) KMT2AMEN1
SCHEMBL5501059 0.75 CTRB1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9864251-B2 Color changeable device ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2018-01-09 US claimed
US-20160246151-A1 COLOR CHANGEABLE DEVICE ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2016-08-25 US claimed
US-9864251-B2 Color changeable device ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2018-01-09 US disclosed
US-20160246151-A1 COLOR CHANGEABLE DEVICE ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2016-08-25 US disclosed
US-20120035341-A1 PROCEDE DE POLYMERISATION PAR VOIE CATALYTIQUE DE 1,4-DIOXANES-2,5-DIONES ET LES POLYMERES CORRESPONDANTS MINASOLVE (FR) 2012-02-09 US disclosed
WO-2010100390-A1 CATALYTIC POLYMERIZATION METHOD FOR 1,4-DIOXANE-2,5-DIONES, AND CORRESPONDING POLYMERS MINASOLVE (FR) 2010-09-10 WO disclosed
WO-2009029242-A1 FUNCTIONALIZATION OF POLYGLYCOLIDES BY 'CLICK' CHEMISTRY MICHIGAN STATE UNIVERSITY (US) 2009-03-05 WO disclosed
WO-2007114946-A2 ACID-SENSITIVE LINKERS FOR DRUG DELIVERY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-10-11 WO disclosed