SCHEMBL5676149

SCHEMBL5676149

CCc1cc(O)c(O)cc1CC

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.68
ALOX12 P18054 4/20 0.68
TRPA1 O75762 1/20 0.48
TDP1 Q9NUW8 4/20 0.46
MEN1 O00255 3/20 0.46
THRB P10828 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 3/20 0.46
RECQL P46063 3/20 0.46
KDM4E B2RXH2 2/20 0.46
POLB P06746 2/20 0.46
MAPT P10636 2/20 0.46
HKDC1 Q2TB90 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
APEX1 P27695 2/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
CACNA1B Q00975 1/20 0.46
APBA1 Q02410 1/20 0.46
MCL1 Q07820 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318708 0.88 ALOX15 (0.56) ALOX15ALOX12TRPA1TDP1MEN1
SCHEMBL6040093 0.88 ALOX15 (0.56) ALOX15ALOX12TRPA1TDP1MEN1
SCHEMBL1760478 0.87 ALOX15 (0.54) ALOX15ALOX12TRPA1TDP1MEN1
SCHEMBL5676840 0.87 ALOX15 (0.56) ALOX15ALOX12TRPA1TDP1MEN1
SCHEMBL3236580 0.85 ALOX15 (0.54) ALOX15ALOX12TRPA1TDP1MEN1
SCHEMBL69488 0.83 ALOX15 (0.52) ALOX15ALOX12TRPA1TDP1MEN1
SCHEMBL6151944 0.83 ALOX15 (0.52) ALOX15ALOX12TDP1MEN1THRB
SCHEMBL5193683 0.83 TYR (0.53) ALOX15ALOX12TDP1MEN1KMT2A
SCHEMBL24456198 0.81 ALOX15 (0.59) ALOX15ALOX12TRPA1TDP1MEN1
SCHEMBL24451032 0.81 ALOX15 (0.59) ALOX15ALOX12TRPA1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020206381-A1 CEPHEM COMPOUNDS WITH LATENT REACTIVE GROUPS AND METHODS OF USING AND MAKING SAME SUTTON LARRY D (US) 2020-10-08 WO disclosed
US-20090048112-A1 Novel Herbicides SYNGENTA LIMITED (GB) 2009-02-19 US disclosed
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III ZHAO BAIYI 2006-02-16 US disclosed
EP-1620447-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III Exxonmobil Chemical Patents Inc. (US) 2006-02-01 EP disclosed
WO-2003102006-A1 SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-12-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060036049-A1 Soluble late transition metal catalysts for olefin oligomerizations III COMT, CD69, SPR ALOX15 907/4885ALOX12 764/4885TRPA1 1914/4885
US-20090048112-A1 Novel Herbicides HAX1, MTX1, CYP4X1 ALOX15 4182/4885ALOX12 3429/4885TRPA1 862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.