SCHEMBL5677307

SCHEMBL5677307

Nc1c(S(=O)(=O)O)cc(S(=O)(=O)O)c2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 4/20 0.59
SENP1 Q9P0U3 4/20 0.59
SUMO2 P61956 3/20 0.59
SUMO1 P63165 3/20 0.59
SENP7 Q9BQF6 3/20 0.59
SENP3 Q9H4L4 2/20 0.56
MEN1 O00255 1/20 0.56
ALDH1A1 P00352 1/20 0.56
APP P05067 1/20 0.56
MAPT P10636 1/20 0.56
THRB P10828 1/20 0.56
HPGD P15428 1/20 0.56
ALOX12 P18054 1/20 0.56
SNCA P37840 1/20 0.56
RECQL P46063 1/20 0.56
BLM P54132 1/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
TTR P02766 1/20 0.53
SLC7A11 Q9UPY5 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6051324 0.86 TTR (0.56) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL1891641 0.86 SENP2 (0.58) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL31222829 0.86 SENP2 (0.58) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL1891262 0.85 MPL (0.57) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL153735 0.85 NT5E (0.59) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL4456435 0.85 SENP2 (0.56) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL4113734 0.83 NT5E (0.57) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL18078576 0.83 SENP2 (0.64) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL7775179 0.83 SENP2 (0.55) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL7207391 0.80 SENP2 (0.56) SENP2SENP1SUMO2SUMO1SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4836959-A SULFONATION OF 1-AMINONAPHTHALENE OR NAPHTHOIC ACID BAYER AKTIENGSELLSCHAFT (DE) 1989-06-06 US claimed
WO-2020142700-A1 BINDING DOMAIN MAPPING AND COMPOUNDS, COMPOSITIONS, COMPLEXES, METHODS, AND KITS RELATED THERETO George Mason Research Foundation, Inc. (US) 2020-07-09 WO disclosed
CN-102566269-B Coloured composition, colour filter and display element JSR株式会社 2016-06-15 CN disclosed
US-20080289124-A1 Reactive Azo Dyes, Methods for the Production Thereof and Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-11-27 US disclosed
US-20080289124-A1 Reactive Azo Dyes, Methods for the Production Thereof and Their Use DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2008-11-27 US disclosed
CN-100363433-C Metal complex colouring agents based on bucherer naphthols DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-01-23 CN disclosed
WO-2007006594-A2 REACTIVE AZO DYES, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 2007-01-18 WO disclosed
EP-1284255-B1 Process for the arylation of olefines SALTIGO GMBH (DE) 2006-11-02 EP disclosed
EP-1328588-B1 METAL COMPLEX COLOURING AGENTS BASED ON BUCHERER NAPHTHOLS DYSTAR TEXTILFARBEN GMBH & CO (DE) 2006-01-11 EP disclosed
US-20050203286-A1 Environmental protection series of reactive dyestuffs and their use EVERLIGHT USA, INC. (US) 2005-09-15 US disclosed
US-4053464-A DISAZO PIGMENTS CONTAINING ETHER SUBSTITUTED ALKOXY CARBONYL GROUPS CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed
US-4046755-A CELLULOSE ETHERS, POLYAMIDES, POLYURETHANES, ACRYLICS CIBA-GEIGY CORPORATION (US) 1977-09-06 US disclosed
US-4031073-A Monoazo pigments containing barbituric acid or thio- or imino-derivatives thereof CIBA-GEIGY CORPORATION (US) 1977-06-21 US disclosed
US-4012371-A Benzinaldazolyl-, quinolonyl-, or phenmorpholonylazo-3-cyano-4-methyl-1,2-[1',2']-benz-[4',5']-imidazolo-6-hydroxypyridine colorants CIBA-GEIGY CORPORATION (US) 1977-03-15 US disclosed
US-4003886-A Tetracarboxylic acid ester substituted disazo pigments CIBA-GEIGY AG (CH) 1977-01-18 US disclosed
US-3988312-A TETRAKISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3963693-A MONOAZO DYES, RED TO YELLOW SHADES, POLYCARBONATES, POLYSTYRENE, POLYVINYL CHLORIDE CIBA-GEIGY CORPORATION (US) 1976-06-15 US disclosed
US-3963694-A AZO PIGMENTS, POLYESTERS, CELLULOSE ETHERS AND ESTERS CIBA-GEIGY CORPORATION (US) 1976-06-15 US disclosed
US-3956266-A DISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080289124-A1 Reactive Azo Dyes, Methods for the Production Thereof and Their Use IK, CYP1A1, ALKBH1 SENP2 3998/4885SENP1 3063/4885SUMO2 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.