Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675844 | 0.81 | TTR (0.46) | ALDH1A1ADORA3RAB9ATTRCA1 | |
| SCHEMBL3880117 | 0.81 | CYP2C9 (0.49) | KDM4EMAPTHSD17B10ALDH1A1MAOA | |
| SCHEMBL5677180 | 0.79 | APP (0.36) | KDM4EMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5680363 | 0.79 | KMT2A (0.42) | KDM4EMAPTHSD17B10CYP3A4SMN1; SMN2 | |
| SCHEMBL5676980 | 0.77 | NQO1 (0.55) | KDM4EMAPTHSD17B10ALDH1A1MAOA | |
| SCHEMBL11416328 | 0.77 | MCL1 (0.52) | KDM4EMAPTHSD17B10ALDH1A1MAOA | |
| SCHEMBL5677951 | 0.76 | MAOA (0.47) | KDM4EMAPTHSD17B10ALDH1A1MAOA | |
| SCHEMBL27687468 | 0.75 | NQO1 (0.53) | KDM4EMAPTHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL5675916 | 0.74 | MAOA (0.57) | KDM4EMAPTHSD17B10ALDH1A1MAOA | |
| SCHEMBL31550331 | 0.73 | ADORA3 (0.62) | KDM4EMAPTHSD17B10ALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1614685-A1 | Process for preparing 2-chloro-6-Halogeno-3-alkyl-4H-chrom en-4-one or 2-chloro-3-alkyl-4H-chromen-4-one derivatives | Bayer CropScience AG (DE) | 2006-01-11 | — | — | EP | claimed |
| EP-1614685-A1 | Process for preparing 2-chloro-6-Halogeno-3-alkyl-4H-chrom en-4-one or 2-chloro-3-alkyl-4H-chromen-4-one derivatives | Bayer CropScience AG (DE) | 2006-01-11 | — | — | EP | disclosed |