SCHEMBL31550331

SCHEMBL31550331

O=c1c(Cl)c(Cl)oc2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.62
MAOA P21397 6/20 0.61
KDM4E B2RXH2 4/20 0.61
MAPT P10636 3/20 0.61
ALDH1A1 P00352 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
HSD17B10 Q99714 2/20 0.61
CYP3A4 P08684 2/20 0.61
GLA P06280 1/20 0.61
HPGD P15428 1/20 0.61
PGAM1 P18669 1/20 0.61
CASP1 P29466 1/20 0.61
CASP7 P55210 1/20 0.61
LMNA P02545 2/20 0.53
TP53 P04637 2/20 0.53
ALOX15 P16050 2/20 0.53
GMNN O75496 1/20 0.53
CYP1A2 P05177 1/20 0.53
POLB P06746 1/20 0.53
ELANE P08246 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445046 0.82 ALDH1A1 (0.56) ADORA3MAOAKDM4EMAPTALDH1A1
SCHEMBL5675916 0.80 MAOA (0.57) ADORA3MAOAKDM4EMAPTALDH1A1
SCHEMBL31584712 0.77 ADORA3 (1.00) ADORA3MAOAKDM4EMAPTALDH1A1
SCHEMBL87774 0.77 ADORA3 (1.00) ADORA3MAOAKDM4EMAPTALDH1A1
Xanthone SCHEMBL29358061 0.77 MAOA (1.00) MAOAKDM4EMAPTALDH1A1SMN1; SMN2
Xanthone SCHEMBL29398266 0.77 MAOA (1.00) MAOAKDM4EMAPTALDH1A1SMN1; SMN2
Xanthone SCHEMBL41161 0.77 MAOA (1.00) MAOAKDM4EMAPTALDH1A1SMN1; SMN2
Xanthone SCHEMBL2354794 0.77 MAOA (1.00) MAOAKDM4EMAPTALDH1A1SMN1; SMN2
SCHEMBL4696277 0.77 MAOA (0.90) MAOAKDM4EMAPTALDH1A1SMN1; SMN2
Xanthone SCHEMBL18556112 0.75 MAOA (0.95) MAOAKDM4EMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775246-A Dichlorochromone compound with helicobacter pylori inhibiting activity and preparation method and application thereof 中国热带农业科学院热带生物技术研究所 2025-04-08 CN claimed
CN-119775246-B Dichlorochromone compound with helicobacter pylori inhibiting activity and preparation method and application thereof 中国热带农业科学院热带生物技术研究所 2026-02-10 CN disclosed
CN-119775246-B Dichlorochromone compound with helicobacter pylori inhibiting activity and preparation method and application thereof 中国热带农业科学院热带生物技术研究所 2026-02-10 CN disclosed
CN-119775246-A Dichlorochromone compound with helicobacter pylori inhibiting activity and preparation method and application thereof 中国热带农业科学院热带生物技术研究所 2025-04-08 CN disclosed
CN-119775246-A Dichlorochromone compound with helicobacter pylori inhibiting activity and preparation method and application thereof 中国热带农业科学院热带生物技术研究所 2025-04-08 CN disclosed
CN-119775246-A Dichlorochromone compound with helicobacter pylori inhibiting activity and preparation method and application thereof 中国热带农业科学院热带生物技术研究所 2025-04-08 CN disclosed