Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253030 | 0.80 | TSHR (0.44) | ENPP2KCNN4KCNA5TSHRCLK4 | |
| SCHEMBL6378412 | 0.78 | TSHR (0.48) | ENPP2KCNN4KCNA5TSHRCLK4 | |
| SCHEMBL5839123 | 0.78 | TSHR (0.52) | ENPP2KCNN4KCNA5TSHRCLK4 | |
| SCHEMBL16484545 | 0.78 | TSHR (0.52) | ENPP2KCNN4KCNA5TSHRCLK4 | |
| SCHEMBL28200866 | 0.76 | LOXL2 (0.44) | ENPP2TSHRNOTUMLOXL2MAOB | |
| SCHEMBL28103471 | 0.76 | KCNN4 (0.40) | ENPP2KCNN4KCNA5TSHRCLK4 | |
| SCHEMBL151270 | 0.75 | ALDH1A1 (0.48) | ENPP2KCNN4KCNA5TSHRCLK4 | |
| SCHEMBL8650222 | 0.74 | ALDH1A1 (0.53) | ENPP2KCNN4KCNA5TSHRMEN1 | |
| SCHEMBL6300638 | 0.74 | FFAR1 (0.47) | ENPP2KCNN4KCNA5TSHRNOTUM | |
| SCHEMBL28971640 | 0.73 | TSHR (0.63) | ENPP2TSHRCLK4NOTUMLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622861-A1 | METHOD OF FORMING A CARBON-HETEROATOM BOND | RHODIA CHIMIE (FR) | 2006-02-08 | — | — | EP | claimed |
| WO-2004101496-A1 | METHOD OF FORMING A CARBON-HETEROATOM BOND | RHODIA CHIMIE (FR) | 2004-11-25 | — | — | WO | claimed |
| EP-1622861-A1 | METHOD OF FORMING A CARBON-HETEROATOM BOND | RHODIA CHIMIE (FR) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004101496-A1 | METHOD OF FORMING A CARBON-HETEROATOM BOND | RHODIA CHIMIE (FR) | 2004-11-25 | — | — | WO | disclosed |