Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22251793 | 0.82 | MEN1 (0.44) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14697483 | 0.79 | KCNA5 (0.46) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9779957 | 0.79 | FFAR1 (0.50) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL6378412 | 0.77 | TSHR (0.48) | FFAR1ALDH1A1MAPTKCNN4KCNA5 | |
| SCHEMBL9899832 | 0.76 | PDK1 (0.42) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5263127 | 0.76 | GSK3B (0.46) | FFAR1ALDH1A1MAPTKCNN4KCNA5 | |
| Bicarbonate SCHEMBL11598627 | 0.75 | GSK3B (0.55) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28103825 | 0.74 | KAT6A (0.36) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5677724 | 0.74 | ENPP2 (0.46) | FFAR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5253030 | 0.74 | TSHR (0.44) | FFAR1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849626-B2 | Aza-amino acid derivatives (factor Xa inhibitors 15) | MERCK PATENT GMBH (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20040034072-A1 | Aza-amino acid derivatives (factor Xa inhibitors 15) | MERCK PATENT GMBH (DE) | 2004-02-19 | — | — | US | disclosed |
| CN-1469860-A | Aza-amino acid derivatives (factor XA-inhibitors 15) | Ĭ��ר���ɷ�����˾ | 2004-01-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034072-A1 | Aza-amino acid derivatives (factor Xa inhibitors 15) | AZI2, F11, SERPINE1 | FFAR1 1052/4885MEN1 1124/4885KMT2A 1175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.