Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | DDO | Q99489 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434363 | 1.00 | MAPK1 (0.61) | MAPK1NPSR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4437503 | 0.84 | MAPK1 (0.58) | MAPK1NPSR1KDM4ETSHRDAO | |
| Bicarbonate SCHEMBL6993932 | 0.83 | MAPK1 (0.61) | MAPK1NPSR1KDM4ETSHRBRD4 | |
| SCHEMBL28431176 | 0.82 | BRD4 (0.53) | MAPK1NPSR1KDM4ETSHRBRD4 | |
| SCHEMBL24852540 | 0.81 | KDM4E (0.59) | MAPK1NPSR1KDM4ETSHRBRD4 | |
| SCHEMBL8306652 | 0.81 | KDM4E (0.59) | MAPK1NPSR1KDM4ETSHRBRD4 | |
| SCHEMBL6402311 | 0.81 | DAO (0.59) | MAPK1NPSR1KDM4ETSHRBRD4 | |
| SCHEMBL3713356 | 0.80 | GRIN2D (0.44) | MAPK1NPSR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL31146173 | 0.80 | DAO (0.58) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL31154599 | 0.79 | KDM4E (0.66) | MAPK1NPSR1KDM4ETSHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988045-B1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | NIELSEN PETER EIGIL (DK) | 2006-02-08 | — | — | EP | disclosed |
| US-6632919-B1 | Bind Watson-Crick base pairs in a double helix; specific for thymidine | Nielsen, Peter (DK) | 2003-10-14 | — | — | US | disclosed |
| US-6617422-B1 | Of given formula; stronger binding and greater specificity than oligonucleotides; useful as probes in cloning, blotting procedures, and in applications such as fluorescence in situ hybridization; can use to detect point mutations | Nielsen, Peter (DK) | 2003-09-09 | — | — | US | disclosed |