Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24852766 | 0.87 | KDM4E (0.65) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL7071513 | 0.83 | IDH1 (0.51) | KDM4EALDH1A1SMN1; SMN2HSD17B10MAPK1 | |
| SCHEMBL7073150 | 0.82 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL3719191 | 0.82 | IDH1 (0.50) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL3715876 | 0.82 | EGFR (0.53) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL30434363 | 0.81 | MAPK1 (0.61) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL5678790 | 0.81 | MAPK1 (0.61) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL8686875 | 0.80 | MTNR1A (0.56) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL24852540 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL3709499 | 0.79 | IDH1 (0.49) | KDM4EALDH1A1SMN1; SMN2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633261-B1 | QUINOLINE-3-ACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | YOSHITOMI PHARMACEUTICAL (JP) | 1999-04-21 | — | — | EP | disclosed |
| US-5543420-A | ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AGENTS; PREVENTION OF ACCUMULATION OF SORBITOL AND GALACTITOL IN MAMMALIAN TISSUE | THE GREEN CROSS CORPORATION (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0633261-A1 | QUINOLINE-3-ACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1995-01-11 | — | — | EP | disclosed |