Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41616 | 0.80 | MMP1 (0.43) | SLC1A3SLC1A2SLC1A1MMP1MMP2 | |
| SCHEMBL3399442 | 0.80 | MMP1 (0.43) | SLC1A3SLC1A2SLC1A1MMP1MMP2 | |
| SCHEMBL5679261 | 0.79 | DPP8 (0.40) | SLC1A3SLC1A2SLC1A1MMP1MMP2 | |
| SCHEMBL6840535 | 0.76 | ATM (0.54) | SLC15A1SLC1A3PSMB5SLC7A5KMT2A | |
| SCHEMBL6840533 | 0.76 | ATM (0.54) | SLC15A1SLC1A3PSMB5SLC7A5KMT2A | |
| SCHEMBL8228297 | 0.76 | MMP1 (0.45) | MMP1MMP2MMP9MMP12ALOX5 | |
| SCHEMBL8818944 | 0.76 | HPGD (0.47) | MMP1MMP2MMP9MMP12KMT2A | |
| SCHEMBL8202887 | 0.76 | HPGD (0.47) | MMP1MMP2MMP9MMP12KMT2A | |
| SCHEMBL6062940 | 0.76 | KIF11 (0.42) | SLC1A3SLC1A2SLC1A1MMP1MMP2 | |
| SCHEMBL10670691 | 0.76 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237925-A1 | MUTANT ER$g(a) AND TEST SYSTEMS FOR TRANSACTIVATION | Sumitomo Chemical Company, Limited (JP) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001042307-A1 | MUTANT ERα AND TEST SYSTEMS FOR TRANSACTIVATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-06-14 | — | — | WO | disclosed |