Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119157 | 0.83 | GABRA1 (0.57) | GABRA1GABRB2HNF4AAKR1B1HMGB1 | |
| SCHEMBL3264280 | 0.80 | GABRA1 (0.60) | GABRA1GABRB2HNF4AAKR1B1HMGB1 | |
| SCHEMBL28177736 | 0.76 | GABRA1 (0.46) | GABRA1GABRB2HNF4AAKR1B1HMGB1 | |
| SCHEMBL497955 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBKDM4EHPGD | |
| SCHEMBL29182577 | 0.75 | FOLH1 (0.47) | GABRA1GABRB2FOLH1ALDH1A1MAPT | |
| SCHEMBL30733380 | 0.75 | FOLH1 (0.47) | GABRA1GABRB2FOLH1ALDH1A1MAPT | |
| SCHEMBL40309 | 0.75 | GABRA1 (0.59) | GABRA1GABRB2HNF4AAKR1B1HMGB1 | |
| SCHEMBL30365997 | 0.75 | GABRA1 (0.59) | GABRA1GABRB2HNF4AAKR1B1HMGB1 | |
| SCHEMBL5178996 | 0.73 | GAA (0.38) | GABRA1GABRB2HMGB1ALDH1A1MAPT | |
| SCHEMBL9615189 | 0.73 | GABRA1 (0.58) | GABRA1GABRB2HNF4AAKR1B1HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430950-B1 | Hydroformylation of unsaturated compounds using polymeric phosphite ligands | INVISTA TECH SARL (US) | 2006-02-22 | — | — | EP | claimed |
| EP-1225978-B1 | HYDROFORMYLATION OF UNSATURATED COMPOUNDS USING POLYMERIC PHOSPHITE LIGANDS | INVISTA TECH SARL (US) | 2005-03-16 | — | — | EP | claimed |
| EP-1216268-B1 | POLYMERIC PHOSPHITE COMPOSITION AND HYDROCYANATION OF UNSATURATED ORGANIC COMPOUNDS AND THE ISOMERIZATION OF UNSATURATED NITRILES | DU PONT (US) | 2003-11-12 | — | — | EP | claimed |