SCHEMBL497955

SCHEMBL497955

C=CCc1cc2cccc(C(=O)O)c2c(C(=O)O)c1CC=C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
POLB P06746 2/20 0.42
MAPT P10636 1/20 0.42
HSD17B10 Q99714 8/20 0.41
PTPN1 P18031 1/20 0.40
ME2 P23368 1/20 0.38
ME1 P48163 1/20 0.38
ME3 Q16798 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KDM4E B2RXH2 7/20 0.37
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
MTNR1A P48039 1/20 0.35
NR4A1 P22736 1/20 0.35
NR4A2 P43354 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2880043 0.82 HSD17B10 (0.47) ALDH1A1POLBMAPTHSD17B10PTPN1
SCHEMBL9062211 0.81 HSD17B10 (0.46) ALDH1A1POLBMAPTHSD17B10PTPN1
SCHEMBL497956 0.79 MEN1 (0.53) ALDH1A1POLBMAPTHSD17B10PTPN1
SCHEMBL1079659 0.77 HSD17B10 (0.45) ALDH1A1POLBHSD17B10PTPN1ME2
SCHEMBL5178996 0.76 GAA (0.38) ALDH1A1POLBMAPTHSD17B10ME2
SCHEMBL5679357 0.75 GABRA1 (0.47) ALDH1A1POLBMAPTHSD17B10PTPN1
SCHEMBL2815958 0.75 HSD17B10 (0.42) ALDH1A1POLBHSD17B10PTPN1ME2
SCHEMBL2361001 0.75 GABRA1 (0.46) ALDH1A1POLBMAPTHSD17B10MEN1
SCHEMBL1137942 0.75 GABRA1 (0.46) ALDH1A1POLBMAPTHSD17B10MEN1
Phthalic Acid SCHEMBL25209633 0.74 ALDH1A1 (0.42) ALDH1A1POLBMAPTHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2350182-A1 METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS HallStar Innovations Corp. (US) 2011-08-03 EP claimed
US-7959834-B2 Alkoxycrylene/metal oxide photostabilized photoactive compositions and methods HALLSTAR INNOVATIONS CORP. (US) 2011-06-14 US claimed
US-20100283015-A1 Alkoxycrylene/Metal Oxide Photostabilized Photoactive Compositions and Methods HALLSTAR INNOVATIONS CORP. (US) 2010-11-11 US claimed
US-7754191-B2 Method of quenching electronic excitation of chromophore-containing organic molecules photoactive compositions HALLSTAR INNOVATIONS CORP. (US) 2010-07-13 US claimed
WO-2010051103-A1 METHOD OF QUENCHING ELECTRONIC EXCITATION OF CHROMOPHORE-CONTAINING ORGANIC MOLECULES IN PHOTOACTIVE COMPOSITIONS HALLSTAR INNOVATIONS CORP. (US) 2010-05-06 WO claimed
US-20090057627-A1 Method of quenching electronic excitation of chromophore-containing organic molecules photoactive compositions HALLSTAR INNOVATIONS CORP. (US) 2009-03-05 US claimed
EP-1633463-B1 PROCESS FOR FORMING AN EMULSION USING MICROCHANNEL PROCESS TECHNOLOGY VELOCYS INC (US) 2007-10-24 EP claimed
EP-1127568-B1 Cosmetic and dermatological light protective formulations containing benzotriazole derivatives and alkylnaphthalates BEIERSDORF AG (DE) 2007-01-24 EP claimed
EP-3812414-A1 HIGH IV MELT PHASE POLYESTER POLYMER CATALYZED WITH ANTIMONY CONTAINING COMPOUNDS GRUPO PETROTEMEX, S.A. DE C.V. (MX) 2021-04-28 EP disclosed
EP-2518096-B1 HIGH IV MELT PHASE POLYESTER POLYMER CATALYZED WITH ANTIMONY CONTAINING COMPOUNDS GRUPO PETROTEMEX SA DE CV (MX) 2021-04-21 EP disclosed
WO-2021064992-A1 HEAT PUMP DEVICE AND ELECTRICAL DEVICE 三菱電機株式会社 2021-04-08 WO disclosed
WO-2021064993-A1 HEAT TRANSFER CONTAINER AND HEAT TRANSFER SYSTEM 三菱電機株式会社 2021-04-08 WO disclosed
WO-2021064990-A1 THERMAL STORAGE DEVICE 三菱電機株式会社 2021-04-08 WO disclosed
WO-2021064989-A1 HEAT PIPE AND ELECTRONIC DEVICE 三菱電機株式会社 2021-04-08 WO disclosed
WO-2003020235-A2 STABILISATION OF OXIDATION-SENSITIVE AND UV-SENSITIVE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2003-03-13 WO disclosed
WO-2003020235-A2 STABILISATION OF OXIDATION-SENSITIVE AND UV-SENSITIVE ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2003-03-13 WO disclosed
WO-2003020232-A2 STABILISATION OF COSMETIC OR DERMATOLOGICAL PREPARATIONS CONTAINING REPELLENT ACTIVE INGREDIENTS BEIERSDORF AG (DE) 2003-03-13 WO disclosed
EP-1129696-A2 Stabilisation of oxidation- and/or UV-sensitive compounds Beiersdorf AG (DE) 2001-09-05 EP disclosed
EP-1127569-A2 Cosmetic and dermatological light protective formulations containing asymmetrically substituted triazine derivatives and alkylnaphthalates Beiersdorf AG (DE) 2001-08-29 EP disclosed
EP-1127568-A2 Cosmetic and dermatological light protective formulations containing benzotriazole derivatives and alkylnaphthalates Beiersdorf AG (DE) 2001-08-29 EP disclosed