SCHEMBL9856474

SCHEMBL9856474

COc1ccc(C=Cc2ccc(O)cc2C)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 0.62
CYP1B1 Q16678 6/20 0.62
PTGS2 P35354 5/20 0.62
PTGS1 P23219 3/20 0.62
KDM4E B2RXH2 3/20 0.62
LMNA P02545 1/20 0.62
ALOX12 P18054 1/20 0.62
ALOX5 P09917 4/20 0.61
CYP1A2 P05177 3/20 0.57
NFE2L2 Q16236 2/20 0.57
TTR P02766 3/20 0.56
NQO2 P16083 3/20 0.56
MAPT P10636 3/20 0.56
ABL1 P00519 2/20 0.56
ABCB1 P08183 2/20 0.56
BCR P11274 2/20 0.56
TUBB1 Q9H4B7 2/20 0.56
MEN1 O00255 2/20 0.56
MAPK1 P28482 2/20 0.56
KMT2A Q03164 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12796879 0.86 NPC1 (0.56) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL5679409 0.86 NPC1 (0.56) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL12091584 0.85 CYP1A1 (0.69) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL19583383 0.83 TUBB1 (0.67) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL19583384 0.83 TUBB1 (0.67) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL30876320 0.81 NFE2L2 (0.63) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL12567384 0.80 PTGS2 (0.77) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL8396882 0.80 PTGS2 (0.77) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL8396878 0.80 PTGS2 (0.77) CYP1A1CYP1B1PTGS2PTGS1KDM4E
SCHEMBL13993018 0.80 TTR (0.56) CYP1A1CYP1B1PTGS2PTGS1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5019451-A Non-centrosymmetric, multi-layer Langmuir-Blodgett films EDISON POLYMER INNOVATION CORP. (US) 1991-05-28 US disclosed