SCHEMBL5679573

SCHEMBL5679573

Cc1ccccc1C(=O)C(O)[C@H]1O[C@H](O)[C@](C)(O)[C@@]1(O)C(=O)c1ccccc1C

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HTT P42858 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5677512 1.00 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3MAPTNPSR1
SCHEMBL5677693 1.00 SLC6A2 (0.31) SLC6A2SLC6A4SLC6A3MAPTNPSR1
SCHEMBL30751007 0.90 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3HTTPIK3CD
Hydrochloric Acid SCHEMBL29878392 0.89 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3MAPTNPSR1
SCHEMBL5707551 0.81 NPC1 (0.32) SLC6A2SLC6A4SLC6A3MAPTNPSR1
SCHEMBL5707623 0.80 NPC1 (0.31) SLC6A2SLC6A4SLC6A3HTT
SCHEMBL5707590 0.80 NPC1 (0.33) SLC6A2SLC6A4SLC6A3MAPTHTT
SCHEMBL5679849 0.78 LMNA (0.33) SLC6A2SLC6A4SLC6A3HTTMEN1
SCHEMBL5680337 0.76
SCHEMBL3395341 0.76 HTT (0.33) SLC6A2SLC6A4SLC6A3MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1631573-A1 PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES INALCO SpA (IT) 2006-03-08 EP disclosed
US-6891036-B2 Process for the preparation of ribofuranose derivatives INALCO S.P.A. (IT) 2005-05-10 US disclosed
WO-2004069851-A1 PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES INALCO S.P.A. (IT) 2004-08-19 WO disclosed
US-20040158059-A1 Process for the preparation of ribofuranose derivatives INALCO S.P.A. (IT) 2004-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158059-A1 Process for the preparation of ribofuranose derivatives RNGTT, RPIA, MRM1 SLC6A2 4866/4885SLC6A4 4584/4885SLC6A3 4798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.