Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 6/20 | 0.46 |
| ▸ | JAK1 | P23458 | 6/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 5/20 | 0.45 |
| ▸ | JAK3 | P52333 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL5683752 | 0.87 | HDAC8 (0.46) | TP53LMNAMEN1ALDH1A1KMT2A | |
| Fumaric Acid SCHEMBL5683755 | 0.87 | HDAC8 (0.46) | TP53LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL5679729 | 0.80 | BRD4 (0.47) | TP53BRD4LMNAMEN1ALDH1A1 | |
| SCHEMBL5681150 | 0.80 | HDAC8 (0.49) | BRD4LMNAALDH1A1HDAC8KDM4E | |
| SCHEMBL4763713 | 0.80 | JAK2 (0.46) | JAK2JAK1USP2LMNATHRB | |
| SCHEMBL17144470 | 0.79 | HDAC8 (0.58) | BRD4LMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL5681214 | 0.77 | TP53 (0.52) | TP53GAAJAK2JAK1BRD4 | |
| SCHEMBL5569508 | 0.77 | POLB (0.66) | GAALMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL5679898 | 0.77 | ALDH1A1 (0.43) | TP53GAAJAK2JAK1BRD4 | |
| Hydrochloric Acid SCHEMBL5572688 | 0.76 | POLB (0.65) | GAALMNAMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403249-B1 | CYCLIC DIAMINE COMPOUNDS BEARING SIX-MEMBERED CYCLIC GROUPS | KOWA CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-1403249-A1 | CYCLIC DIAMINE COMPOUNDS BEARING SIX-MEMBERED CYCLIC GROUPS | Kowa Co., Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6509329-B1 | Inhibitory effects on both cell adhesion and cell infiltration and is useful as a medicine for prevention or treatment of diseases such as allergy, asthma, rheumatism, arteriosclerosis and inflammation | KOWA CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |