SCHEMBL5680149

SCHEMBL5680149

Cc1ccccc1C(=O)C(O)[C@H]1O[C@H](OC(=O)c2ccc(Cl)cc2)[C@](C)(OC(=O)c2ccc(Cl)cc2)[C@@]1(O)C(=O)c1ccccc1C

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.34
UTS2R Q9UKP6 1/20 0.32
UBE2D3 P61077 1/20 0.31
NPC1 O15118 1/20 0.31
ALOX15 P16050 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 1/20 0.31
LMNA P02545 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
P2RX7 Q99572 1/20 0.30
POLB P06746 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5682286 0.93 NPC1 (0.32) NPC1RAB9AMAPTALDH1A1
SCHEMBL5680337 0.83
SCHEMBL5707623 0.75 NPC1 (0.31) NPC1HTTRAB9AALDH1A1
SCHEMBL5707590 0.75 NPC1 (0.33) NPC1HTTRAB9AL3MBTL1MAPT
SCHEMBL5677512 0.72 SLC6A2 (0.31) HTTMAPT
SCHEMBL5679573 0.72 SLC6A2 (0.31) HTTMAPT
SCHEMBL5677693 0.72 SLC6A2 (0.31) HTTMAPT
SCHEMBL30751007 0.71 SLC6A2 (0.32) NPC1HTTRAB9APOLBALDH1A1
SCHEMBL5707551 0.70 NPC1 (0.32) NPC1HTTRAB9AMAPTPOLB
Hydrochloric Acid SCHEMBL29878392 0.70 SLC6A2 (0.32) HTTMAPTPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1631573-A1 PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES INALCO SpA (IT) 2006-03-08 EP claimed
US-6891036-B2 Process for the preparation of ribofuranose derivatives INALCO S.P.A. (IT) 2005-05-10 US claimed
WO-2004069851-A1 PROCESS FOR THE PREPARATION OF RIBOFURANOSE DERIVATIVES INALCO S.P.A. (IT) 2004-08-19 WO claimed
US-20040158059-A1 Process for the preparation of ribofuranose derivatives INALCO S.P.A. (IT) 2004-08-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040158059-A1 Process for the preparation of ribofuranose derivatives RNGTT, RPIA, MRM1 MGLL 3426/4885UTS2R 3517/4885UBE2D3 2969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.