Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644829 | 0.88 | DNM1L (0.41) | GAAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL1840692 | 0.85 | GAA (0.40) | ARGAATP53HTTKMT2A | |
| SCHEMBL4703944 | 0.83 | HTT (0.40) | ARTDP1TP53HTTKMT2A | |
| SCHEMBL5680354 | 0.82 | NPC1 (0.45) | ARHTTKMT2AMEN1MAPT | |
| SCHEMBL5676062 | 0.80 | AR (0.41) | ARGAATDP1TP53HTT | |
| SCHEMBL5676515 | 0.79 | GAA (0.36) | GAATDP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1844197 | 0.76 | TDP1 (0.38) | ARGAATDP1TP53HTT | |
| SCHEMBL1841466 | 0.75 | SIGMAR1 (0.37) | ARTDP1TP53HTTMAPT | |
| SCHEMBL5896808 | 0.74 | GAA (0.42) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1662655 | 0.74 | AR (0.51) | ARTDP1TP53KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124479-B2 | Oligopyrroles as antagonists of islet amyloid polypeptide oligomerization | NEW YORK UNIVERSITY (US) | 2021-09-21 | — | — | US | disclosed |
| US-20190016679-A1 | OLIGOPYRROLES AS ANTAGONISTS OF ISLET AMYLOID POLYPEPTIDE OLIGOMERIZATION | NEW YORK UNIVERSITY (US) | 2019-01-17 | — | — | US | disclosed |
| US-7141680-B2 | Aromatic compounds possessing antifungal or antibacterial activity | GENELABS TECHNOLOGIES, INC. | 2006-11-28 | — | — | US | disclosed |
| EP-1556035-A4 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECH INC (US) | 2006-09-13 | — | — | EP | disclosed |
| EP-1556035-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004026264-A2 | NOVEL AROMATIC COMPOUNDS POSSESSING ANTIFUNGAL OR ANTIBACTERIAL ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2004-04-01 | — | — | WO | disclosed |
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | SMITHKLINE BEECHAM CORPORATION | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040063645-A1 | Novel aromatic compounds possessing antifungal or antibacterial activity | ZC3HAV1, TYR, ZC3HAV1L | AR 2351/4885GAA 21/4885KEAP1 768/4885 |
| US-20190016679-A1 | OLIGOPYRROLES AS ANTAGONISTS OF ISLET AMYLOID POLYPEPTIDE OLIGOMERIZATION | IAPP, APP, AMY2A | AR 3667/4885GAA 954/4885KEAP1 1876/4885 |
| US-11124479-B2 | Oligopyrroles as antagonists of islet amyloid polypeptide oligomerization | IAPP, APP, AMY2A | AR 3667/4885GAA 954/4885KEAP1 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.