Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RELA | Q04206 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653356 | 0.86 | CCNE1 (0.39) | CCNE1CDK2CDK5NPC1LMNA | |
| SCHEMBL5653949 | 0.81 | CCNE1 (0.55) | CCNE1CDK2CDK5NPC1LMNA | |
| SCHEMBL10864137 | 0.81 | FFAR2 (0.40) | CCNE1CDK2CDK5NPC1LMNA | |
| SCHEMBL10864376 | 0.80 | PSEN1 (0.36) | CCNE1CDK2CDK5NPC1LMNA | |
| SCHEMBL21229046 | 0.77 | SMN1; SMN2 (0.43) | CCNE1CDK2CDK5ALDH1A1TSHR | |
| SCHEMBL5652094 | 0.75 | RAB9A (0.54) | NPC1LMNARAB9ATP53SMN1; SMN2 | |
| SCHEMBL5653937 | 0.75 | CCNE1 (0.38) | CCNE1CDK2CDK5NPC1LMNA | |
| SCHEMBL2652269 | 0.73 | FFAR2 (0.57) | CCNE1CDK2CDK5NPC1LMNA | |
| SCHEMBL21229056 | 0.73 | NAMPT (0.38) | TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL2650712 | 0.72 | SMN1; SMN2 (0.54) | CCNE1CDK2CDK5NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640369-A1 | THIAZOLIMINE COMPOUND AND OXAZOLIMINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-03-29 | — | — | EP | disclosed |