Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 4/20 | 0.39 |
| ▸ | SCD | O00767 | 3/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680451 | 0.86 | CCNE1 (0.39) | CCNE1CDK2CDK5SCDALDH1A1 | |
| SCHEMBL5653949 | 0.79 | CCNE1 (0.55) | CCNE1CDK2CDK5ALDH1A1NPC1 | |
| SCHEMBL10864137 | 0.79 | FFAR2 (0.40) | CCNE1CDK2CDK5SCDALDH1A1 | |
| SCHEMBL10864376 | 0.75 | PSEN1 (0.36) | CCNE1CDK2CDK5SCDALDH1A1 | |
| SCHEMBL5652094 | 0.73 | RAB9A (0.54) | NPC1LMNARAB9ATP53MEN1 | |
| SCHEMBL5684644 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5653937 | 0.73 | CCNE1 (0.38) | CCNE1CDK2CDK5SCDALDH1A1 | |
| SCHEMBL2652269 | 0.71 | FFAR2 (0.57) | CCNE1CDK2CDK5NPC1LMNA | |
| SCHEMBL12027314 | 0.71 | KMT2A (0.55) | CCNE1CDK2CDK5AURKASCD | |
| SCHEMBL2650712 | 0.70 | SMN1; SMN2 (0.54) | CCNE1CDK2CDK5ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105908-A1 | Thiazolimine compound and oxazolimine compound | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-05-10 | — | — | US | disclosed |
| EP-1640369-A1 | THIAZOLIMINE COMPOUND AND OXAZOLIMINE COMPOUND | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105908-A1 | Thiazolimine compound and oxazolimine compound | CMA1, TH, NPR3 | CCNE1 290/4885CDK2 488/4885CDK5 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.