Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22233464 | 0.83 | BCL2 (0.48) | BCL2BCL2L1NR1H2HTR2ACALM1 | |
| SCHEMBL5681255 | 0.82 | NR1H2 (0.45) | NR1H2ALDH1A1HSD17B10TDP1CA1 | |
| SCHEMBL9822747 | 0.80 | MEN1 (0.56) | BCL2BCL2L1NR1H2ALDH1A1HSD17B10 | |
| SCHEMBL30988956 | 0.80 | CA2 (0.50) | BCL2BCL2L1HTR2ACA1CA2 | |
| SCHEMBL5700547 | 0.80 | BCL2 (0.45) | BCL2BCL2L1NR1H2HTR2ACALM1 | |
| SCHEMBL13413605 | 0.80 | BCL2 (0.45) | BCL2BCL2L1NR1H2HTR2ACALM1 | |
| SCHEMBL407413 | 0.80 | CA2 (0.50) | BCL2BCL2L1HTR2ACA1CA2 | |
| SCHEMBL29740732 | 0.80 | BCL2 (0.50) | BCL2BCL2L1NR1H2HTR2ACALM1 | |
| SCHEMBL28375617 | 0.80 | ELANE (0.47) | BCL2BCL2L1NR1H2HTR2ACALM1 | |
| SCHEMBL7738158 | 0.80 | BCL2 (0.50) | BCL2BCL2L1NR1H2HTR2ACALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115636802-A | Resveratrol acryloyl piperazine benzene sulfonamide derivative and preparation and application thereof | 合肥学院 | 2023-01-24 | — | — | CN | disclosed |
| CN-109020922-B | Preparation method of cyclic sulfonamide compound | 陕西师范大学 | 2022-01-04 | — | — | CN | disclosed |
| EP-2721006-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HELMINTH INFECTIONS | E. I. Du Pont de Nemours and Company (US) | 2014-04-23 | — | — | EP | disclosed |
| WO-2012177668-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING HELMINTH INFECTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-12-27 | — | — | WO | disclosed |
| EP-0932600-B1 | SULFONAMIDE SUBSTITUTED ASPARTIC ACID INTERLEUKIN-1BETA CONVERTING ENZYME INHIBITORS | WARNER LAMBERT CO (US) | 2006-02-08 | — | — | EP | disclosed |
| US-6083981-A | USEFUL FOR TREATMENT OF STROKE, INFLAMMATORY DISEASES, SEPTIC SHOCK, REPERFUSION INJURY, ALZHEIMER'S DISEASE, SHIGELLOSIS | WARNER-LAMBERT COMPANY (US) | 2000-07-04 | — | — | US | disclosed |
| US-6054487-A | ADMINISTERING AN INTERLEUKIN-ONE BETA CONVERTING ENZYME SUFFICIENT TO INHIBIT PRODUCTION OF GAMMA-INTERFERON | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |