SCHEMBL5700547

SCHEMBL5700547

[NH]S(=O)(=O)c1ccccc1Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.45
BCL2L1 Q07817 1/20 0.45
HTR2A P28223 1/20 0.42
CALM1 P0DP23 1/20 0.42
CTRC Q99895 3/20 0.41
NR1H2 P55055 1/20 0.40
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
CA12 O43570 1/20 0.38
CA14 Q9ULX7 1/20 0.38
FAAH O00519 1/20 0.38
PRSS1 P07477 1/20 0.38
PRSS2 P07478 1/20 0.38
ELANE P08246 1/20 0.38
PRTN3 P24158 1/20 0.38
PRSS3 P35030 1/20 0.38
CA5A P35218 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22233464 0.83 BCL2 (0.48) BCL2BCL2L1HTR2ACALM1CTRC
SCHEMBL7738158 0.80 BCL2 (0.50) BCL2BCL2L1HTR2ACALM1CTRC
SCHEMBL30988956 0.80 CA2 (0.50) BCL2BCL2L1HTR2ACA1CA2
SCHEMBL28375617 0.80 ELANE (0.47) BCL2BCL2L1HTR2ACALM1CTRC
SCHEMBL407413 0.80 CA2 (0.50) BCL2BCL2L1HTR2ACA1CA2
SCHEMBL29740732 0.80 BCL2 (0.50) BCL2BCL2L1HTR2ACALM1CTRC
SCHEMBL13413605 0.80 BCL2 (0.45) BCL2BCL2L1HTR2ACALM1CTRC
SCHEMBL5680692 0.80 BCL2 (0.45) BCL2BCL2L1HTR2ACALM1CTRC
SCHEMBL11744449 0.78 BCL2 (0.44) BCL2BCL2L1HTR2ACALM1CTRC
Hydrochloric Acid SCHEMBL3517386 0.78 CA1 (0.49) BCL2BCL2L1HTR2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1146037-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS NIPPON SODA CO (JP) 2006-06-21 EP disclosed
US-6410749-B1 REACTING A CARBONYL COMPOUND WITH ORGANOMETALLIC COMPOUND NIPPON SODA CO., LTD. (JP) 2002-06-25 US disclosed
EP-1146037-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS NIPPON SODA CO., LTD. (JP) 2001-10-17 EP disclosed