Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433659 | 0.95 | SLC6A1 (0.41) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL6581856 | 0.95 | SLC6A1 (0.41) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL21324676 | 0.92 | ALDH1A1 (0.40) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL20156421 | 0.92 | ALDH1A1 (0.40) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL9115694 | 0.90 | ALDH1A1 (0.38) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL24912524 | 0.89 | ALDH1A1 (0.47) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL6426932 | 0.89 | ALDH1A1 (0.47) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL791582 | 0.89 | — | — | |
| SCHEMBL22540086 | 0.89 | ALDH1A1 (0.47) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL16877745 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504338-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | RAPT Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| WO-2023196432-A1 | CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF | RAPT THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| CN-116102543-A | GLP-1R agonist, synthesis method and application thereof | 江南大学 | 2023-05-12 | — | — | CN | disclosed |
| EP-3941459-A1 | QUINOLINE AND QUINAZOLINE COMPOUNDS AND METHODS OF USE THEREOF | Stingray Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| CN-113924092-A | Quinoline and quinazoline compounds and methods of use thereof | 斯汀格瑞治疗股份有限公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-108250128-A | Compound as potassium channel modulating agents | 江苏先声药业有限公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-103694163-A | Compounds as Potassium Channel Modulators | SHANGHAI SIMCERE DRUG RES CO LTD | 2014-04-02 | — | — | CN | disclosed |
| EP-1060785-B1 | Interfacially polymerized, bipiperidine-polyamide membranes for reverse osmosis and/or nanofiltration and process for making the same | HYDRANAUTICS (US) | 2006-04-05 | — | — | EP | disclosed |
| EP-1339691-A1 | NOVEL COMPOUNDS | GlaxoSmithKline S.p.A. (IT) | 2003-09-03 | — | — | EP | disclosed |
| CN-1439004-A | Indole derivatives for the treatment of central nervous system disorders | LUNDBECK & CO AS H (DK) | 2003-08-27 | — | — | CN | disclosed |
| US-6464873-B1 | POLYFUNCTIONAL AROMATIC OR CYCLOALIPHATIC ACYL HALIDE REACTANT; HIGH FLUX RATES AND LOW PRESSURES WITH HIGH SULFATE REJECTION. | HYDRANAUTICS | 2002-10-15 | — | — | US | disclosed |
| WO-2002044154-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE SPA (IT) | 2002-06-06 | — | — | WO | disclosed |
| EP-1060785-A1 | Interfacially polymerized, bipiperidine-polyamide membranes for reverse osmosis and/or nanofiltration and process for making the same | HYDRANAUTICS (US) | 2000-12-20 | — | — | EP | disclosed |
| US-5215967-A | AMINOACID DERIVATIVES INHIBITING RENIN | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-06-01 | — | — | US | disclosed |