Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | FABP6 | P51161 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679426 | 0.85 | FABP6 (0.53) | FABP6ALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL3827667 | 0.83 | ALDH1A1 (0.58) | XDHFABP6ALDH1A1MEN1KMT2A | |
| SCHEMBL129665 | 0.81 | FABP6 (0.60) | FABP6ALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL117352 | 0.81 | BACE1 (0.54) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL5681861 | 0.81 | ALDH1A1 (0.47) | FABP6ALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL5679180 | 0.81 | TAAR1 (0.50) | FABP6ALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL5679580 | 0.81 | MAP4K4 (0.49) | XDHALDH1A1MEN1KMT2AMASP2 | |
| Bromide SCHEMBL2381776 | 0.80 | BACE1 (0.53) | ALDH1A1MEN1KMT2AMASP2NUDT1 | |
| SCHEMBL11911271 | 0.78 | NPC1 (0.59) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL119520 | 0.78 | XDH (0.56) | XDHALDH1A1MEN1KMT2AMASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341769-B1 | BACTERIAL GYRASE INHIBITORS AND USES THEREOF | VERTEX PHARMA (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |