Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679441 | 0.85 | MASP2 (0.47) | MEN1KMT2AMASP2ALDH1A1NUDT1 | |
| SCHEMBL3827667 | 0.83 | ALDH1A1 (0.58) | MEN1KMT2AMASP2ALDH1A1NUDT1 | |
| SCHEMBL214295 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AMASP2ALDH1A1NUDT1 | |
| SCHEMBL5681861 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AMASP2ALDH1A1NUDT1 | |
| SCHEMBL5680955 | 0.81 | XDH (0.52) | MEN1KMT2AMASP2ALDH1A1NUDT1 | |
| SCHEMBL117352 | 0.81 | BACE1 (0.54) | TAAR1MEN1KMT2AMASP2ALDH1A1 | |
| SCHEMBL30798863 | 0.81 | TNKS2 (0.48) | TAAR1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL119520 | 0.81 | XDH (0.56) | MEN1KMT2AMASP2ALDH1A1NUDT1 | |
| SCHEMBL3716080 | 0.81 | MAP4K4 (0.49) | MEN1KMT2AMASP2ALDH1A1NUDT1 | |
| Bromide SCHEMBL2381776 | 0.80 | BACE1 (0.53) | TAAR1MEN1KMT2AMASP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620413-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098494-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-18 | — | — | WO | disclosed |