Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7837580 | 0.99 | HRH3 (0.53) | HRH3KCNH2TLR9TLR7ACHE | |
| SCHEMBL6390332 | 0.94 | MAOB (0.52) | HRH3KCNH2 | |
| SCHEMBL28032867 | 0.89 | HRH3 (0.62) | HRH3 | |
| SCHEMBL30979868 | 0.88 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL30209183 | 0.88 | HRH3 (0.49) | HRH3 | |
| SCHEMBL3067381 | 0.88 | HRH3 (0.54) | HRH3KCNH2 | |
| SCHEMBL5679317 | 0.84 | HRH3 (0.45) | HRH3TLR9 | |
| SCHEMBL6689692 | 0.84 | HRH3 (0.45) | HRH3TLR9TLR7 | |
| SCHEMBL31115682 | 0.82 | HRH3 (0.62) | HRH3KCNH2TLR9TLR7ACHE | |
| SCHEMBL10732685 | 0.82 | HRH3 (0.62) | HRH3KCNH2TLR9TLR7ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731415-B | Quinazoline-4-piperazine dithioformate and preparation method and purpose thereof | UNIV CAPITAL NORMAL | 2014-12-31 | — | — | CN | disclosed |
| EP-1620104-A1 | THERAPEUTIC AGENTS COMPRISING AN ANTI-ANGIOGENIC AGENT IN COMBINATION WITH AN SRC-INHIBITOR AND THEIR THERAPEUTIC USE | Astrazeneca AB (SE) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004098604-A1 | THERAPEUTIC AGENTS COMPRISING AN ANTI-ANGIOGENIC AGENT IN COMBINATION WITH AN SRC-INHIBITOR AND THEIR THERAPEUTIC USE | ASTRAZENECA AB (SE) | 2004-11-18 | — | — | WO | disclosed |