SCHEMBL5682229

SCHEMBL5682229

CC(=CC(CCC(=CC(C)=Nc1ccc(C)cc1)Nc1ccc(C)cc1)=Nc1ccc(C)cc1)Nc1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
SIGMAR1 Q99720 2/20 0.42
TDP1 Q9NUW8 1/20 0.34
POLB P06746 3/20 0.33
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
SCN1A P35498 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN3A Q9NY46 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5838724 0.83 GRIN2D (0.54) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5838730 0.83 GRIN2D (0.54) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5681448 0.67 MAPT (0.56) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15312985 0.67 MAPT (0.56) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5681453 0.67 MAPT (0.56) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15312983 0.67 MAPT (0.56) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL15312987 0.67 MAPT (0.56) MAPTGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4109679 0.65 GRIN2D (0.63) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4109674 0.65 GRIN2D (0.63) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL5032779 0.65 HTR3E (0.48) MAPTGRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362066-B1 CATALYST FOR POLYMERIZATION OF OLEFIN AND THE METHOD OF POLYMERIZATION OF OLEFIN USING THE SAME SAMSUNG GENERAL CHEMICALS CO (KR) 2006-02-15 EP disclosed
EP-1362066-A4 CATALYST FOR POLYMERIZATION OF OLEFIN AND THE METHOD OF POLYMERIZATION OF OLEFIN USING THE SAME SAMSUNG GENERAL CHEMICALS CO (KR) 2004-09-15 EP disclosed
EP-1362066-A1 CATALYST FOR POLYMERIZATION OF OLEFIN AND THE METHOD OF POLYMERIZATION OF OLEFIN USING THE SAME Samsung General Chemicals Co., Ltd. (KR) 2003-11-19 EP disclosed
US-6590046-B2 Reacting a Mg(R'mAl(OR')nR)2 compound wherein R and R' are alkyl groups, n=1, 2 or 3, and m=3-n, with a cyclopentadiene based ligand to form an intermediate, reacting it with amide based ligand, then reacting with titanium compound SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2003-07-08 US disclosed
US-20020115800-A1 Catalyst for polymerization of olefin and the method of polymerization of olefin using the same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2002-08-22 US disclosed
WO-2002050130-A1 CATALYST FOR POLYMERIZATION OF OLEFIN AND THE METHOD OF POLYMERIZATION OF OLEFIN USING THE SAME SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) 2002-06-27 WO disclosed