Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.36 |
| ▸ | INPP5A | Q14642 | 2/20 | 0.36 |
| ▸ | INPP5B | P32019 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21969523 | 0.90 | GPR84 (0.42) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL4521607 | 0.87 | INPPL1 (0.48) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27745872 | 0.84 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27692904 | 0.81 | KMT2A (0.35) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30332098 | 0.80 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6251330 | 0.79 | HTT (0.46) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| Pyrene SCHEMBL21437358 | 0.77 | ALDH1A1 (0.52) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL27947558 | 0.77 | MAPT (0.43) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9973244 | 0.77 | ALDH1A1 (0.46) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL30935962 | 0.74 | MAPT (0.39) | KMT2AMEN1ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092406-A1 | FUNCTIONALLY-ENHANCED XNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-03-20 | — | — | US | disclosed |
| EP-4377463-A1 | FUNCTIONALLY-ENHANCED XNA | The Regents of the University of California (US) | 2024-06-05 | — | — | EP | disclosed |
| US-11858953-B2 | Compositions and methods for synthesis of phosphorylated molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-02 | — | — | US | disclosed |
| WO-2023009898-A1 | FUNCTIONALLY-ENHANCED XNA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-02 | — | — | WO | disclosed |
| US-20210332070-A1 | Compositions and Methods for Synthesis of Phosphorylated Molecules | UNIV CALIFORNIA (US) | 2021-10-28 | — | — | US | disclosed |
| US-11021497-B2 | Compositions and methods for synthesis of phosphorylated molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200239500-A1 | Compositions and Methods for Synthesis of Phosphorylated Molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-07-30 | — | — | US | disclosed |
| WO-2019195494-A1 | COMPOSITIONS AND METHODS FOR SYNTHESIS OF PHOSPHORYLATED MOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-10 | — | — | WO | disclosed |
| EP-1501505-B1 | USE OF (3-(2-ETHYLPHENYL)-5-METHOXYPHENYL)-1H- 1,2,4 -TRIAZOLE FOR THE TREATMENT OF AUTOIMMUNE DISEASES | SIGMA TAU IND FARMACEUTI (IT) | 2006-01-18 | — | — | EP | disclosed |
| US-20050026980-A1 | Use of (3-(2-ethylphenyl)-5-methoxyphenyl)-1H-[1,2,4]-triazole for the treatment of autoimmune diseases | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-02-03 | — | — | US | disclosed |
| EP-1501505-A1 | USE OF (3-(2-ETHYLPHENYL)-5-METHOXYPHENYL)-1H- 1,2,4 -T RIAZOLE FOR THE TREATMENT OF AUTOIMMUNE DISEASES | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2005-02-02 | — | — | EP | disclosed |
| US-6797722-B2 | Use of 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole for the treatment of autoimmune diseases | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-09-28 | — | — | US | disclosed |
| WO-2003092681-A1 | USE OF (3-(2-ETHYLPHENYL)-5-METHOXYPHENYL)-1H-[1,2,4]-TRIAZOLE FOR THE TREATMENT OF AUTOIMMUNE DISEASES | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-11-13 | — | — | WO | disclosed |
| US-20030207931-A1 | USE OF 3-(2-ETHYLPHENYL)-5-(3-METHOXYPHENYL)-1H-1,2,4-TRIAZOLE FOR THE TREATMENT OF AUTOIMMUNE DISEASES | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858953-B2 | Compositions and methods for synthesis of phosphorylated molecules | PIK3CA, CHAMP1, TYMP | KMT2A 2972/4885MEN1 2132/4885ALDH1A1 4371/4885 |
| US-20200239500-A1 | Compositions and Methods for Synthesis of Phosphorylated Molecules | PIK3CA, CHAMP1, TYMP | KMT2A 2972/4885MEN1 2132/4885ALDH1A1 4371/4885 |
| US-11021497-B2 | Compositions and methods for synthesis of phosphorylated molecules | PIK3CA, CHAMP1, TYMP | KMT2A 2972/4885MEN1 2132/4885ALDH1A1 4371/4885 |
| US-20210332070-A1 | Compositions and Methods for Synthesis of Phosphorylated Molecules | PIK3CA, CHAMP1, TYMP | KMT2A 2972/4885MEN1 2132/4885ALDH1A1 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.