SCHEMBL4521607

SCHEMBL4521607

O=P(O)(O)Oc1ccc2ccc3cccc4ccc1c2c34

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 6/20 0.48
INPP5A Q14642 4/20 0.48
INPP5B P32019 2/20 0.48
AKT1 P31749 1/20 0.47
SRC P12931 3/20 0.44
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 6/20 0.41
HPGD P15428 6/20 0.41
HSD17B10 Q99714 5/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 3/20 0.40
MAPT P10636 1/20 0.40
USP2 O75604 1/20 0.40
PDE3A Q14432 1/20 0.40
CYP1A2 P05177 4/20 0.39
CYP1A1 P04798 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21969523 0.89 GPR84 (0.42) INPPL1INPP5AINPP5BSRCKMT2A
SCHEMBL5682245 0.87 KMT2A (0.38) INPPL1INPP5AINPP5BAKT1SRC
SCHEMBL30332098 0.85 ALDH1A1 (0.44) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL27745872 0.83 ALDH1A1 (0.41) INPPL1INPP5AINPP5BSRCKMT2A
SCHEMBL9456245 0.83 INPPL1 (0.46) INPPL1INPP5AINPP5BAKT1SRC
SCHEMBL9973244 0.82 ALDH1A1 (0.46) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL27947558 0.82 MAPT (0.43) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL27692904 0.80 KMT2A (0.35) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL9973243 0.78 CYP1A2 (0.40) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL2472730 0.77 INPPL1 (0.52) INPPL1INPP5AINPP5BAKT1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111116646-A Self-assembly interface material 苏州和颂生化科技有限公司 2020-05-08 CN disclosed
CN-106299138-A Synthesis of material with phosphate group and preparation of self-assembled film on oxide surface 南京工业大学 2017-01-04 CN disclosed
US-20140295403-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2014-10-02 US disclosed
US-8632966-B2 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2014-01-21 US disclosed
US-20130217041-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2013-08-22 US disclosed
US-8377686-B2 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2013-02-19 US disclosed
US-20090117600-A1 Detection of biological molecules by differential partitioning of enzyme substrates and products QUEEN'S UNIVERSITY AT KINGSTON (CA) 2009-05-07 US disclosed
US-7402426-B2 Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits QUEEN'S UNIVERSITY AT KINGSTON (CA) 2008-07-22 US disclosed
EP-1539986-B1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS UNIV KINGSTON (CA) 2007-07-18 EP disclosed
EP-1539986-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS Queen's University at Kingston (CA) 2005-06-15 EP disclosed
US-20040106164-A1 Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-06-03 US disclosed
WO-2004027084-A1 DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2004-04-01 WO disclosed