Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256211 | 0.98 | TDP1 (0.50) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| SCHEMBL8641932 | 0.83 | TDP1 (0.52) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| SCHEMBL28256272 | 0.83 | TDP1 (0.52) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| SCHEMBL8157521 | 0.80 | TDP1 (0.48) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| Sorbitol SCHEMBL628565 | 0.78 | LMNA (0.65) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| SCHEMBL7590412 | 0.78 | LMNA (0.46) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| SCHEMBL14413769 | 0.75 | MGAM (0.42) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| SCHEMBL14377638 | 0.75 | MGAM (0.42) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| Mannitol SCHEMBL20572201 | 0.75 | LMNA (0.69) | TDP1LMNAL3MBTL1MGAMPDE4A | |
| Sorbitol SCHEMBL3227835 | 0.75 | LMNA (0.69) | TDP1LMNAL3MBTL1MGAMPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213316-B1 | Polyhydric alcohol-modified silicone and cosmetic material containing same | SHINETSU CHEMICAL CO (JP) | 2006-03-08 | — | — | EP | disclosed |
| US-7001971-B2 | Polyhydric alcohol-modified silicone and cosmetic material containing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-02-21 | — | — | US | disclosed |
| EP-1213316-A2 | Polyhydric alcohol-modified silicone and cosmetic material containing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |