Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5683340 | 1.00 | GAA (0.35) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL8407050 | 0.87 | GAA (0.38) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL8407051 | 0.87 | GAA (0.38) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL5686103 | 0.84 | TRPA1 (0.35) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL5686106 | 0.84 | TRPA1 (0.35) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL5683291 | 0.83 | TSHR (0.31) | — | |
| SCHEMBL5683289 | 0.83 | TSHR (0.31) | — | |
| SCHEMBL9796681 | 0.83 | GAA (0.40) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL9796686 | 0.83 | GAA (0.40) | GAAMGAMSIMGAM2TRPA1 | |
| SCHEMBL8969178 | 0.83 | MGAM (0.34) | GAAMGAMSIMGAM2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832873-B1 | Preparation of cyclopropane esters | SYNGENTA LTD (GB) | 2006-03-08 | — | — | EP | disclosed |
| EP-0793638-B1 | PREPARATION OF CYCLOPROPANE ESTERS | ZENECA LTD (GB) | 1999-06-30 | — | — | EP | disclosed |
| CN-1220255-A | Preparation of cyclopropane esters | ZENECA LTD (GB) | 1999-06-23 | — | — | CN | disclosed |
| EP-0700375-B1 | PREPARATION OF CYCLOPROPANE ESTERS | ZENECA LTD (GB) | 1998-12-23 | — | — | EP | disclosed |
| EP-0700373-B1 | PREPARATION OF HALOGENATED ALCOHOLS | ZENECA LTD (GB) | 1998-04-22 | — | — | EP | disclosed |
| EP-0832873-A1 | Preparation of cyclopropane esters | ZENECA LIMITED (GB) | 1998-04-01 | — | — | EP | disclosed |
| US-5731475-A | Preparation of cyclopropane esters | ZENECA LIMITED (GB) | 1998-03-24 | — | — | US | disclosed |
| US-5723649-A | Preparation of cyclopropane esters | ZENECA LIMITED (GB) | 1998-03-03 | — | — | US | disclosed |
| US-5670697-A | Preparation of cyclopropane esters | ZENECA LIMITED (GB) | 1997-09-23 | — | — | US | disclosed |
| EP-0793638-A1 | PREPARATION OF CYCLOPROPANE ESTERS | ZENECA LIMITED (GB) | 1997-09-10 | — | — | EP | disclosed |
| US-5527972-A | Preparation and use of halogenated alcohols | ZENECA LIMITED (GB) | 1996-06-18 | — | — | US | disclosed |
| WO-1996016018-A1 | PREPARATION OF CYCLOPROPANE ESTERS | ZENECA LIMITED (GB) | 1996-05-30 | — | — | WO | disclosed |
| EP-0700375-A1 | PREPARATION OF CYCLOPROPANE ESTERS | ZENECA LIMITED (GB) | 1996-03-13 | — | — | EP | disclosed |
| EP-0700373-A1 | PREPARATION OF HALOGENATED ALCOHOLS | ZENECA LIMITED (GB) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027951-A1 | PREPARATION OF CYCLOPROPANE ESTERS | ZENECA LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |
| WO-1994027942-A1 | PREPARATION OF HALOGENATED ALCOHOLS | ZENECA LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |