Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLI1 | P08151 | 1/20 | 0.46 |
| ▸ | GLI2 | P10070 | 1/20 | 0.46 |
| ▸ | HAT1 | O14929 | 5/20 | 0.45 |
| ▸ | EP300 | Q09472 | 5/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5695724 | 1.00 | ULK1 (0.51) | ULK1LTA4HEPHX2KMT2AGLI1 | |
| SCHEMBL5684479 | 1.00 | ULK1 (0.51) | ULK1LTA4HEPHX2KMT2AGLI1 | |
| SCHEMBL5682167 | 0.93 | LTA4H (0.46) | ULK1LTA4HEPHX2KMT2AGLI1 | |
| SCHEMBL5681613 | 0.91 | EPHX2 (0.52) | LTA4HEPHX2KMT2AHAT1EP300 | |
| SCHEMBL5680327 | 0.91 | EPHX2 (0.52) | LTA4HEPHX2KMT2AHAT1EP300 | |
| SCHEMBL5680330 | 0.91 | EPHX2 (0.52) | LTA4HEPHX2KMT2AHAT1EP300 | |
| SCHEMBL5684150 | 0.90 | MAOB (0.51) | KMT2AHTR2CHTR2B | |
| SCHEMBL5684137 | 0.90 | MAOB (0.51) | KMT2AHTR2CHTR2B | |
| SCHEMBL5697043 | 0.88 | ADRB3 (0.56) | LTA4HEPHX2KMT2AHAT1EP300 | |
| SCHEMBL5697044 | 0.88 | ADRB3 (0.56) | LTA4HEPHX2KMT2AHAT1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044186-B9 | SUBSTITUTED 2-BENZYLAMINO-2-PHENYL-ACETAMIDE COMPOUNDS | NEWRON PHARM SPA (IT) | 2006-06-21 | — | — | EP | disclosed |
| EP-1044186-B1 | SUBSTITUTED 2-BENZYLAMINO-2-PHENYL-ACETAMIDE COMPOUNDS | NEWRON PHARM SPA (IT) | 2006-03-08 | — | — | EP | disclosed |