SCHEMBL5684576

SCHEMBL5684576

Fc1cccc2c1Cc1c(F)cccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.47
DRD2 P14416 1/20 0.41
DRD3 P35462 1/20 0.41
NOS3 P29474 1/20 0.41
NOS2 P35228 1/20 0.41
TYR P14679 1/20 0.39
SRD5A1 P18405 1/20 0.39
PKM P14618 1/20 0.37
PKLR P30613 1/20 0.37
HTR1A P08908 3/20 0.36
HTR7 P34969 3/20 0.36
CYP19A1 P11511 2/20 0.36
MAPK1 P28482 1/20 0.36
CYP11B1 P15538 1/20 0.36
CYP11B2 P19099 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517854 1.00 PGR (0.47) PGRDRD2DRD3NOS3NOS2
SCHEMBL4359047 0.84 PNMT (0.53) PGRDRD2DRD3HTR1AHTR7
SCHEMBL5866517 0.82 PGR (0.41) PGRDRD2DRD3NOS3NOS2
SCHEMBL29634952 0.80 SRD5A1 (0.42) PGRDRD2NOS3NOS2TYR
SCHEMBL29389674 0.80 NOS3 (0.37) PGRDRD2DRD3NOS3NOS2
SCHEMBL24262469 0.80 NOS3 (0.37) PGRDRD2DRD3NOS3NOS2
SCHEMBL5866457 0.78 PGR (0.42) PGRNOS3NOS2TYRHTR1A
SCHEMBL9811064 0.77 CA1 (0.47) PGRNOS3NOS2HTR1AHTR7
SCHEMBL5684563 0.76 PGR (0.41) PGRNOS3NOS2TYR
SCHEMBL5684561 0.76 PGR (0.41) PGRNOS3NOS2TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024035392-A1 CARBONATE COMPOUNDS AS ACTIVITY LIMITING AGENTS IN ZIEGLER-NATTA CATALYST COMPOSITIONS FOR OLEFIN POLYMERIZATION FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2024-02-15 WO disclosed
CN-114350379-A Novel liquid crystal compound and preparation method and application thereof 北京八亿时空液晶科技股份有限公司 2022-04-15 CN disclosed
EP-1349822-B1 FLUORINATED AROMATIC COMPOUNDS AND THE USE OF THE SAME IN LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 2016-09-28 EP disclosed
CN-100422124-C Fused ring compound DAINIPPON INK & CHEMICALS (JP) 2008-10-01 CN disclosed
US-7067179-B1 Fused ring compound DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-06-27 US disclosed
EP-1201632-B1 FUSED RING COMPOUND DAINIPPON INK & CHEMICALS (JP) 2006-03-29 EP disclosed
US-7018685-B2 Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures MERCK PATENT GMBH (DE) 2006-03-28 US disclosed
US-20040124399-A1 Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures MERCK PATENT GMBH (DE) 2004-07-01 US disclosed
EP-1349822-A1 FLUORINATED AROMATIC COMPOUNDS AND THE USE OF THE SAME IN LIQUID CRYSTAL MIXTURES CLARIANT INTERNATIONAL LTD. (CH) 2003-10-08 EP disclosed
CN-1371347-A Fused ring compound DAINIPPON INK & CHEMICALS (JP) 2002-09-25 CN disclosed
WO-2002055463-A1 FLUORINATED AROMATIC COMPOUNDS AND THE USE OF THE SAME IN LIQUID CRYSTAL MIXTURES CLARIANT INTERNATIONAL LTD. (CH) 2002-07-18 WO disclosed
EP-1201632-A1 FUSED RING COMPOUND DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040124399-A1 Fluorinated aromatic compounds and the use of the same in liquid crystal mixtures AFF1, AFF2, FLI1 PGR 4497/4885DRD2 683/4885DRD3 476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.