Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5684615 | 0.86 | TSHR (0.57) | CASP1TSHRPDE10ACNR1CNR2 | |
| SCHEMBL6573367 | 0.86 | PDE10A (0.63) | CASP1TSHRPDE10AANPEPDPP4 | |
| SCHEMBL5687574 | 0.83 | PLAU (0.50) | CASP1TSHRPDE10AALDH1A1PLAU | |
| SCHEMBL5688012 | 0.82 | CASP1 (0.53) | CASP1TSHRPDE10AANPEPDPP4 | |
| SCHEMBL5687631 | 0.82 | CASP1 (0.63) | CASP1TSHRPDE10AALDH1A1CA1 | |
| SCHEMBL5684875 | 0.82 | TSHR (0.57) | CASP1TSHRPDE10AANPEPDPP4 | |
| SCHEMBL6011175 | 0.81 | CASP1 (0.47) | CASP1TSHRPDE10AANPEPDPP4 | |
| Hydrochloric Acid SCHEMBL5685021 | 0.81 | CASP1 (0.52) | CASP1TSHRPDE10AANPEPDPP4 | |
| SCHEMBL5687598 | 0.81 | TSHR (0.45) | CASP1TSHRPDE10AALDH1A1PLAU | |
| SCHEMBL6011387 | 0.81 | CASP1 (0.54) | CASP1TSHRPDE10AANPEPDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7077872-B2 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AG (DE) | 2006-07-18 | — | — | US | disclosed |
| EP-1418879-B1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-14 | — | — | US | disclosed |
| EP-1418879-A1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003017955-A1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | KRT18, S100P, ALDH7A1 | CASP1 2849/4885TSHR 2675/4885PDE10A 4235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.