Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | CASP1 | P29466 | 2/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572188 | 0.86 | PDE10A (0.61) | TSHRCASP1PDE10APLA2G7RAB9A | |
| SCHEMBL1461185 | 0.85 | PLA2G7 (0.55) | TSHRCASP1PDE10APLA2G7RAB9A | |
| SCHEMBL28053536 | 0.85 | ALDH1A1 (0.56) | TSHRCASP1PDE10ARAB9ASMN1; SMN2 | |
| SCHEMBL5688012 | 0.85 | CASP1 (0.53) | TSHRCASP1PDE10APLA2G7RAB9A | |
| Hydrochloric Acid SCHEMBL6788783 | 0.85 | PDE10A (0.59) | TSHRCASP1PDE10APLA2G7RAB9A | |
| SCHEMBL4229761 | 0.83 | PTPRC (0.61) | TSHRCASP1PDE10APLA2G7RAB9A | |
| Hydrochloric Acid SCHEMBL5685021 | 0.83 | CASP1 (0.52) | TSHRCASP1PDE10APLA2G7RAB9A | |
| SCHEMBL5687750 | 0.83 | SMN1; SMN2 (0.50) | TSHRCASP1PDE10ARAB9ASMN1; SMN2 | |
| SCHEMBL5685015 | 0.82 | CASP1 (0.59) | TSHRCASP1PDE10APLA2G7MAPT | |
| SCHEMBL6011421 | 0.82 | CASP1 (0.52) | TSHRCASP1PDE10APLA2G7RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7077872-B2 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AG (DE) | 2006-07-18 | — | — | US | disclosed |
| EP-1418879-B1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 2004-10-14 | — | — | US | disclosed |
| EP-1418879-A1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | Wella Aktiengesellschaft (DE) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003017955-A1 | OXIDATION HAIR DYES CONTAINING 3-AMINOPHENOL DERIVATIVES, AND NOVEL 3-AMINOPHENOL DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040200010-A1 | Oxidation hair dyes containing 3-aminophenol derivatives, and novel 3-aminophenol derivatives | KRT18, S100P, ALDH7A1 | TSHR 2675/4885CASP1 2849/4885PDE10A 4235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.