Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.54 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011399 | 0.92 | CASP1 (0.50) | CASP1DPP4ANPEPALDH1A1CD44 | |
| SCHEMBL6011175 | 0.87 | CASP1 (0.47) | CASP1DPP4ANPEPALDH1A1CD44 | |
| SCHEMBL6011221 | 0.84 | NR3C1 (0.45) | CASP1DPP4ANPEPALDH1A1CYP3A4 | |
| SCHEMBL6011411 | 0.82 | CYP3A4 (0.43) | CASP1ALDH1A1CYP3A4TSHRRECQL | |
| SCHEMBL6011236 | 0.82 | CASP1 (0.48) | CASP1DPP4ANPEPALDH1A1CD44 | |
| SCHEMBL6011533 | 0.82 | CASP1 (0.48) | CASP1DPP4ANPEPALDH1A1CD44 | |
| SCHEMBL6011421 | 0.81 | CASP1 (0.52) | CASP1DPP4ANPEPALDH1A1CYP3A4 | |
| SCHEMBL5685015 | 0.81 | CASP1 (0.59) | CASP1DPP4ANPEPALDH1A1CYP3A4 | |
| SCHEMBL23609094 | 0.79 | CYP3A4 (0.57) | ALDH1A1CD44CYP3A4TSHRTDP1 | |
| SCHEMBL3785419 | 0.79 | ALDH1A1 (0.46) | CASP1DPP4ANPEPALDH1A1CD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355619-B1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AG (DE) | 2006-12-06 | — | — | EP | claimed |
| EP-1355619-B1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AG (DE) | 2006-12-06 | — | — | EP | disclosed |
| US-7056347-B2 | Coloring agents for keratin fibers containing (1,1′-biphenyl)-2,4-diamine derivatives in addition to novel (1,1′-biphenyl)-2,4-diamine-derivatives | WELLA AG (DE) | 2006-06-06 | — | — | US | disclosed |
| EP-1355619-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | Wella Aktiengesellschaft (DE) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062307-A1 | COLOURING AGENTS FOR KERATIN FIBRES CONTAINING (1.1'-BIPHENYL)-2.4-DIAMINE DERIVATIVES IN ADDITION TO NOVEL (1.1'-BIPHENYL)-2.4-DIAMINE-DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-08-15 | — | — | WO | disclosed |