⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171368 | 0.65 | — | — | |
| SCHEMBL11190048 | 0.64 | NOS1 (0.36) | — | |
| SCHEMBL5049668 | 0.62 | — | — | |
| SCHEMBL1083170 | 0.61 | — | — | |
| SCHEMBL5514042 | 0.52 | — | — | |
| SCHEMBL4058540 | 0.52 | THRB (0.30) | — | |
| SCHEMBL27209141 | 0.52 | THRB (0.30) | — | |
| SCHEMBL27209144 | 0.52 | THRB (0.30) | — | |
| SCHEMBL11720388 | 0.51 | — | — | |
| SCHEMBL5406262 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224177-B1 | PROCESS FOR PREPARING OXAZOLINES FROM TETRAHYDROFURANS | AGOURON PHARMA (US) | 2004-02-11 | — | — | EP | claimed |
| US-20030023092-A1 | Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors | BORER BENNETT C (US) | 2003-01-30 | — | — | US | claimed |
| US-6472534-B2 | TREATING TETRAHYDROFURAN DERIVATIV WITH AN OXOPHILIC ELECTROPHILIC REAGENT IN A MANNER THAT IS EFFECTIVE TO PROVIDE THE OXAZOLINE COMPOUND | AGOURON PHARMACEUTICALS, INC. | 2002-10-29 | — | — | US | claimed |
| EP-1224177-A1 | PROCESS FOR PREPARING OXAZOLINES FROM TETRAHYDROFURANS | AGOURON PHARMACEUTICALS, INC. (US) | 2002-07-24 | — | — | EP | claimed |
| US-20020038033-A1 | Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors | BORER BENNETT C (US) | 2002-03-28 | — | — | US | claimed |
| WO-2001029013-A1 | PROCESS FOR PREPARING OXAZOLINES FROM TETRAHYDROFURANS | AGOURON PHARMACEUTICALS, INC. (US) | 2001-04-26 | — | — | WO | claimed |
| CN-102757684-B | Bei replaces oxazoline compound or Bei replaces oxazoline derivant | Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) | 2015-11-18 | — | — | CN | disclosed |
| CN-102757679-B | Comprise Bei and replace the ink composite that oxazoline compound or Bei replace oxazoline derivant | Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) | 2015-10-28 | — | — | CN | disclosed |
| US-9109124-B2 | Solid ink compositions comprising semicrystalline oligomer resins | XEROX CORPORATION (US) | 2015-08-18 | — | — | US | disclosed |
| US-9044512-B2 | Amino alcohol cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140323548-A1 | NOVEL AMINO ALCOHOL CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2014-10-30 | — | — | US | disclosed |
| US-8802863-B2 | Amino alcohol cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2014-08-12 | — | — | US | disclosed |
| US-8500260-B2 | Ink compositions incorporating substituted oxazoline compounds or substituted oxazoline derivatives | XEROX CORPORATION (US) | 2013-08-06 | — | — | US | disclosed |
| WO-2001066536-A1 | PROCESS FOR THE PREPARATION OF CITALOPRAM | RESOLUTION CHEMICALS LIMITED (GB) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001029013-A1 | PROCESS FOR PREPARING OXAZOLINES FROM TETRAHYDROFURANS | AGOURON PHARMACEUTICALS, INC. (US) | 2001-04-26 | — | — | WO | disclosed |
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |
| EP-0536713-A1 | Oxazole and imidazole derivatives as prostaglandin analogs | E.R. SQUIBB & SONS, INC. (US) | 1993-04-14 | — | — | EP | disclosed |
| US-4780405-A | Carbonic anhydrase inhibitor-tagged nucleic acid probes | SISKA DIAGNOSTICS, INC. (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0210021-A2 | Carbonic anhydrase inhibitor-tagged nucleic acid probes | SISKA DIAGNOSTICS,INC. (US) | 1987-01-28 | — | — | EP | disclosed |
| US-4042546-A | Reactive polyester-amide polymers as co-reactants or curing agents for polyepoxides and polyisocyanates | SIMON ELI | 1977-08-16 | — | — | US | disclosed |